CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16968
Family Name Dihydrofolate reductase inhibitor 5-[[4-[2-[4-(4-aminophenyl)sulfonylanilino]ethoxy]-3-methoxyphenyl]methyl]pyrimidine-2,4-diamine family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00440032 Functional Category Bioactive
Superfamily Beta-2 adrenergic receptor and Beta-3 adrenergic receptor Binder Superfamily
Class Class 834

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
SB1518 family 7 103
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Prostaglandin D2 receptor ligand 3-[2-methoxy-6-[2-(4-methoxyp... 2 12
ALK tyrosine kinase receptor and Insulin receptor ligand N-[(1... 3 20
Epidermal growth factor receptor and Receptor tyrosine-protein... 6 9
Growth hormone secretagogue receptor type 1 ligand SureCN63605... 5 7
Growth hormone secretagogue receptor type 1 ligand SureCN63645... 1 0
ALK tyrosine kinase receptor and Insulin receptor ligand cerit... 2 0
Glucokinase inhibitor AGN-PC-03ZE4O family 4 5


External ID

Functional Category

Molecule Name

CFAMM00440032 CHEMBL425506 Bioactive 5-[[4-[2-[4-(4-aminophenyl)sulfonylanilino]ethoxy]-3-methoxyphenyl]methyl]pyrimidine-2,4-diamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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