CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16984
Family Name Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-aminobutyric acid receptor subunit alpha-1 ligand (Z)-3-(4-chloroanilino)-2-(2-chlorobenzoyl)-N-cyclobutylprop-2-enamide family
No. of Seeds 2 No. of Other Members 8
Family Centroid CFAMM00440088 Functional Category Bioactive
Superfamily Microtubule-associated protein tau and Cytochrome P450 3A4 Binder Superfamily
Class Class 1375

Cousin Family NamesSeedsMembers
Cruzipain Inhibitor 5-chloro-1-(4-chloro-benzyl)-1h-indole-2,3... 3 13
Liver carboxylesterase 1 Inhibitor 4-chloro-1h-indole-2,3-dion... 3 7
Liver carboxylesterase 1 Inhibitor 7-chloro-1h-indole-2,3-dion... 6 5
Phospholipase D1 Inhibitor Halopemide Family 17 111
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 12
Metabotropic glutamate receptor 5 Ligand N-(3-acetamidophenyl)... 4 20
Adenosine receptor A2a Ligand 1-amino-4-chloroanthracene-9,10-... 1 3
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Vasopressin V2 receptor ligand [2-chloro-4-(prop-2-enylamino)p... 3 14
Cellular tumor antigen p53 and Inositol monophosphatase 1 inhi... 1 12
Melanocortin receptor 4 ligand SureCN6183720 family 2 5
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
P2X purinoceptor 7 inhibitor AGN-PC-050YNC family 1 6
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
C-C chemokine receptor type 5 ligand AC1MHP8Y family 1 0
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 4 6
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00440082 CHEMBL9662 Bioactive 2-amino-N-[4-chloro-2-(2-chlorobenzoyl)phenyl]acetamide
CFAMM00440088 CHEMBL426916 Bioactive (Z)-3-(4-chloroanilino)-2-(2-chlorobenzoyl)-N-cyclobutylprop-2-enamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26824 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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