CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1700
Family Name Neuronal acetylcholine receptor subunit beta-4 and Neuronal acetylcholine receptor subunit alpha-3 ligand N-[5-[2-[[(1R,5R,6S)-3-azabicyclo[3.2.1]octan-6-yl]oxy]phenyl]pyridin-3-yl]methanesulfonamide;hydrochloride family
No. of Seeds 6 No. of Other Members 4
Family Centroid CFAMM00160296 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Ligand Sarizotan Superfamily
Class Class 1129

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Nicotinic acetylcholine receptor Ligand AZD0328 Family 11 97
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Nicotinic acetylcholine receptor Ligand Dianicline Family 6 13
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Reverse transcriptase Inhibitor 3'thiacytidine Family 4 29
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 12 3
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
Fatty-acid amide hydrolase 1 Inhibitor Pyridin-3-yl 4-butoxybe... 10 5
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 7 1
Neuronal acetylcholine receptor subunit alpha-3 and Neuronal a... 2 0
Neuronal acetylcholine receptor subunit beta-4 and Neuronal ac... 1 0
Somatostatin receptor type 5 ligand AGN-PC-080TDB family 10 14
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 8 8
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 11 4
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 4
Cytochrome P450 11B2, mitochondrial and Cytochrome P450 11B1, ... 9 7
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 16 19
Neuronal acetylcholine receptor subunit alpha-2 and Neuronal a... 6 1
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 5 0
Potassium voltage-gated channel subfamily KQT member 2 ligand ... 3 4
Prothrombin and Coagulation factor X inhibitor N-[3-[(3-fluoro... 1 8
Renin inhibitor SureCN6042213 family 2 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(2,3-... 2 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 23 5
Sodium/hydrogen exchanger 1 inhibitor 2-[(E)-[7-(2-chloropheny... 2 0
Glutamate receptor ionotropic, NMDA 2B and Cytochrome P450 2D6... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00326577 CHEMBL1209243 Bioactive N-[5-[2-[[(1R,5R,6S)-3-azabicyclo[3.2.1]octan-6-yl]oxy]phenyl]pyridin-3-yl]ethanesulfonamide;hydrochloride
CFAMM00326576 CHEMBL1209242 Bioactive N-[5-[2-[[(1S,5S,6R)-3-azabicyclo[3.2.1]octan-6-yl]oxy]phenyl]pyridin-3-yl]methanesulfonamide;hydrochloride
CFAMM00326575 CHEMBL1209244 Bioactive N-[5-[2-[[(1R,5R,6S)-3-azabicyclo[3.2.1]octan-6-yl]oxy]phenyl]pyridin-3-yl]propane-2-sulfonamide;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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