CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17022
Family Name Angiotensin-converting enzyme inhibitor SureCN7263641 family
No. of Seeds 2 No. of Other Members 11
Family Centroid CFAMM00440191 Functional Category Bioactive with Natural Product
Superfamily Prostaglandin D2 receptor and Angiotensin-converting enzyme Binder Superfamily
Class Class 107

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Penicillin binding protein inhibitor β-lactam aminopenicillin ... 12 359
Sodium channel protein type 5 subunit alpha Ligand Mephenytoin... 5 51
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Angiotensin-converting enzyme Inhibitor Quinapril Family 3 105
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 7 54
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Prothrombin Inhibitor Ximelagatran Family 5 48
Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
Dopamine reuptake Inhibitor Amineptine Family 2 5
Integrin alpha-V and Integrin beta-3 Inhibitor C[rgd-(s)-alpha... 19 95
Prothrombin Inhibitor Efegatran Family 9 47
Neprilysin Inhibitor Thiorphan Family 41 68
Neuromedin-K receptor Ligand Senktide Family 15 22
Prothrombin Inhibitor D-leucyl-n-(4-carbamimidoylbenzyl)-l-pro... 13 44
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Penicillin-binding protein 1B Inhibitor N-benzoyl-d-alanine Fa... 1 40
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
Integrin alpha-V and Integrin beta-3 Inhibitor Cyclo-[-arg-gly... 5 38
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Integrin beta-3 Inhibitor L-709780 Family 9 10
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Beta-secretase 1 Inhibitor Glu-leu-asp-leu-(choh-ch2)-ala-ala-... 15 11
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Chymase Inhibitor Chymostatin Family 2 3
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Azum... 3 10
Integrin alpha-V Inhibitor C[rgdf-(3s)-carboxymorpholine] Family 10 2
Caspase-4 and Cathepsin D Inhibitor Grassystatin A Family 24 6
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Angiotensin-converting enzyme inhibitor (S)-1-((S)-5-benzamido... 5 2
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-3-[... 13 17
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-1-b... 3 4
Carboxypeptidase B and Carboxypeptidase B2 inhibitor (2S)-7-am... 3 9
NS3 and Non-structural protein 4A inhibitor (4S)-4-[[(2S)-3-ca... 1 1
Survival motor neuron protein inhibitor CHEMBL1323700 family 1 4
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7285564... 1 2
Prostaglandin D2 receptor ligand AGN-PC-09QGM4 family 1 0
Cathepsin K and Cathepsin S inhibitor 1-benzyl-3-[(2S)-1-[[cya... 1 0
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7961093... 1 0
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 4 inhibitor (2... 3 10
Integrin beta-3 and Integrin alpha-V inhibitor 2-[(1R,5S,11S,1... 8 2
P2X purinoceptor 7 inhibitor SureCN8516206 family 5 1
Type-2 angiotensin II receptor ligand SureCN3515167 family 2 0
Angiotensin-converting enzyme and Angiotensin-converting enzym... 1 0
Histone deacetylase 1 and Histone deacetylase 8 inhibitor meth... 1 3
Ribonucleoside-diphosphate reductase large subunit and Ribonuc... 1 0
Beta-secretase 1 inhibitor (2R)-4-amino-2-[[(2S)-2-[[(2S)-2-[[... 2 1
NS3 inhibitor 6-[[(2S)-1-[[(2S)-1-[(2S)-2-[[1-(cyclopropylamin... 2 0
Smoothened homolog inhibitor N-cyclohexyl-1,3-dioxo-2-[(1S,2R)... 2 0
(2S)-2-[(3aR,6aS)-2,5-dioxo-3,3a,6,6a-tetrahydro-1H-imidazo[4,... 1 0
Putative NP ZINC08764865 Family 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00440192 CHEMBL99798 Bioactive SureCN7270378
CFAMM00440191 CHEMBL430689 Bioactive SureCN7263641

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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