CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17052
Family Name Carbonic anhydrase 2 inhibitor benzyl 2-[[2-[[(2S)-3-phenyl-2-[(4-sulfamoylbenzoyl)amino]propanoyl]amino]acetyl]amino]acetate family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00440318 Functional Category Bioactive
Superfamily Cathepsin B and Cathepsin L1 Binder Superfamily 3
Class Class 3206

Cousin Family NamesSeedsMembers
ATP-sensitive inward rectifier potassium channel 10 Ligand Ace... 2 64
Thymidylate synthase Inhibitor Sp-876 Family 7 117
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Cathepsin S inhibitor ethyl 2-[[3-[[(2S)-3-cyclohexyl-2-[(4-me... 2 9
Integrin beta-3 and Integrin alpha-IIb inhibitor (2R)-2-(benze... 4 13
Cathepsin B and Cathepsin L1 inhibitor 3-[[(2R)-2-cyano-2-[[(2... 3 4
Pol polyprotein inhibitor Lysine Sulfonamide 11c family 3 73
Pol polyprotein inhibitor AC1LA9K7 family 7 23
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6429531 f... 2 0
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 5 2
72 kDa type IV collagenase and Stromelysin-1 inhibitor (3R)-3-... 3 2
Calpain-1 catalytic subunit and Cathepsin B inhibitor (2R)-N-[... 2 2
Neutrophil elastase inhibitor (1,1,3-trioxo-1,2-benzothiazol-2... 2 6
Integrin alpha-V inhibitor (2R)-3-[(2-methoxybenzoyl)amino]-2-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00440313 CHEMBL63926 Bioactive benzyl 2-[[2-[[(2S)-2-phenyl-2-[(4-sulfamoylbenzoyl)amino]acetyl]amino]acetyl]amino]acetate
CFAMM00440318 CHEMBL433456 Bioactive benzyl 2-[[2-[[(2S)-3-phenyl-2-[(4-sulfamoylbenzoyl)amino]propanoyl]amino]acetyl]amino]acetate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27698 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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