CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17082
Family Name Thymidylate synthase inhibitor (2S)-2-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[4-[(4-chloro-2-methylquinolin-6-yl)methyl-prop-2-ynylamino]-2-fluorobenzoyl]amino]butanoyl]amino]butanoyl]amino]pentanedioic acid;2,2,2-trifluoroacetic acid family
No. of Seeds 1 No. of Other Members 7
Family Centroid CFAMM00440459 Functional Category Bioactive
Superfamily Thymidylate synthase Binder Superfamily 3
Class Class 3182

Cousin Family NamesSeedsMembers
Integrin alpha-V and Integrin beta-3 Inhibitor SB-223245 Family 27 36
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Endothelin B receptor Ligand IRL-2500 Family 34 87
Dihydrofolate reductase and Thymidylate synthase inhibitor 2-[... 10 5
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-[(2,6... 3 14
Folylpolyglutamate synthase, mitochondrial and Dihydrofolate r... 3 0
Thymidylate synthase inhibitor (2S)-2-[[4-[(2-chloro-4-methoxy... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00440459 CHEMBL436448 Bioactive (2S)-2-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[4-[(4-chloro-2-methylquinolin-6-yl)methyl-prop-2-ynylamino]-2-fluorobenzoyl]amino]butanoyl]amino]butanoyl]amino]pentanedioic acid;2,2,2-trifluoroacetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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