CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM171
Family Name Transient receptor potential cation channel subfamily V member 1 ligand SureCN4020659 family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00308365 Functional Category Bioactive
Superfamily Transient receptor potential cation channel subfamily V member 1 Ligand A-425619 Superfamily
Class Class 825

Cousin Family NamesSeedsMembers
Glutamate dehydrogenase inhibitor quinoline derivative Chloroq... 7 189
D(2) dopamine receptor ligand ergot alkaloid Cabergoline Family 5 74
D(2) dopamine receptor Ligand Sertindole Family 3 173
Histamine H1 receptor Ligand Triprolidine Family 19 316
Transient receptor potential cation channel subfamily V member... 15 158
Transient receptor potential cation channel subfamily V member... 16 295
Amg 423 family 7 47
ABC294640 family 5 75
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
5-hydroxytryptamine receptor 2B Ligand Sb 206553 Family 14 21
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Cytochrome... 9 40
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
DNA-dependent protein kinase catalytic subunit Inhibitor 2-mor... 2 6
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-(3-cyano-... 2 4
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 2 4
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 9
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhib... 1 13
Metabotropic glutamate receptor 5 ligand [(E)-(1,2-dicyclohexy... 1 4
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 1 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 8
Metabotropic glutamate receptor 2 ligand AGN-PC-00A1HD family 2 0
Prostaglandin E synthase and Aldo-keto reductase family 1 memb... 3 12
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075BGV ... 1 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 1 4
C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[3-[(4-fluo... 3 2
Macrophage colony-stimulating factor 1 receptor and Vascular e... 2 3
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(4-py... 9 0
Sterol O-acyltransferase 1 inhibitor SureCN7073167 family 4 2
Rho-associated protein kinase 2 and Rho-associated protein kin... 1 0
Reverse transcriptase/RNaseH inhibitor (4s)-6-chloro-4-cyclopr... 5 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00308363 CHEMBL427111 Bioactive Isoquinoline Analogue, 42
CFAMM00308361 CHEMBL104757 Bioactive SureCN4022734
CFAMM00308365 CHEMBL103590 Bioactive SureCN4020659

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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