CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17134
Family Name Renin inhibitor (1R,5S)-N-[(2-chlorophenyl)methyl]-7-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-N,3-dimethyl-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide family
No. of Seeds 9 No. of Other Members 0
Family Centroid CFAMM00440700 Functional Category Bioactive
Superfamily Renin Binder Superfamily 3
Class Class 3124

Cousin Family NamesSeedsMembers
Urotensin-2 receptor Ligand SB-436811 Family 6 71
Renin inhibitor (1S,5S)-7-[4-[3-(2-chloro-3,6-difluorophenoxy)... 11 16
Renin inhibitor AGN-PC-07ZC01 family 12 16
Renin inhibitor SureCN1472318 family 4 1
Renin and Cytochrome P450 3A4 inhibitor (3R,4S)-N-[[2-chloro-5... 28 3
Renin inhibitor (1R,5S)-N-cyclopropyl-N-[(3-methoxy-2-methylph... 4 4
Substance-P receptor ligand AGN-PC-075NP5 family 4 8
Vasopressin V1a receptor ligand 1-(4-chlorophenyl)-N-[(2R)-1-[... 2 8
Melanocortin receptor 4 ligand [(3R,4S)-4-(4-chlorophenyl)-1-p... 5 8
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 15
Melanocortin receptor 4 and Melanocortin receptor 5 ligand 3-a... 2 2
Renin inhibitor (1R,5S)-3-acetyl-N-cyclopropyl-N-[(2,3-dichlor... 11 0
Renin inhibitor SureCN5073976 family 6 0
Renin inhibitor AGN-PC-00CP4L family 2 0
Renin inhibitor 3-(4-amino-4-oxobutanoyl)-N-[(2-chlorophenyl)m... 2 0
Renin inhibitor (1R,5S)-3-acetyl-7-[4-[3-(2-bromo-5-fluorophen... 3 0
Renin inhibitor (1R,5S)-N-[(2-chlorophenyl)methyl]-7-[4-[3-[(2... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00440700 CHEMBL500205 Bioactive (1R,5S)-N-[(2-chlorophenyl)methyl]-7-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-N,3-dimethyl-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440699 CHEMBL502200 Bioactive (1R,5S)-3-acetyl-N-[(2-chlorophenyl)methyl]-7-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-N-methyl-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440698 CHEMBL508748 Bioactive (1R,5S)-3-benzylsulfonyl-N-[(2-chlorophenyl)methyl]-7-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-N-methyl-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440697 CHEMBL507083 Bioactive (1R,5S)-3-acetyl-N-[(4-chlorophenyl)methyl]-N-cyclopropyl-7-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440696 CHEMBL504443 Bioactive (1R,5S)-3-acetyl-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-7-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440702 CHEMBL504403 Bioactive (1R,5S)-N-[(2-chlorophenyl)methyl]-7-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-N-methyl-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440695 CHEMBL508158 Bioactive (1R,5S)-3-[2-(4-chlorophenyl)acetyl]-N-[(2-chlorophenyl)methyl]-7-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-N-methyl-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440701 CHEMBL443469 Bioactive (1R,5S)-3-acetyl-N-[(2-chlorophenyl)methyl]-N-cyclopropyl-7-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440694 CHEMBL449458 Bioactive (1R,5S)-3-acetyl-N-[(3-chlorophenyl)methyl]-N-cyclopropyl-7-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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