CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17138
Family Name Renin inhibitor (1R,5S)-3-acetyl-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-7-[4-(2-phenoxyethoxy)phenyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide family
No. of Seeds 11 No. of Other Members 0
Family Centroid CFAMM00440730 Functional Category Bioactive
Superfamily Renin Binder Superfamily 3
Class Class 3124

Cousin Family NamesSeedsMembers
Renin inhibitor (1S,5S)-7-[4-[3-(2-chloro-3,6-difluorophenoxy)... 11 16
Renin inhibitor (1R,5R)-3-[4-[3-(2-chloro-3,6-difluorophenoxy)... 5 2
Renin inhibitor AGN-PC-07ZC01 family 12 16
Renin inhibitor SureCN1472318 family 4 1
Renin and Cytochrome P450 3A4 inhibitor (3R,4S)-N-[[2-chloro-5... 28 3
Renin inhibitor (1R,5S)-N-cyclopropyl-N-[(3-methoxy-2-methylph... 4 4
Renin inhibitor (1R,5S)-N-[(2-chlorophenyl)methyl]-7-[4-[3-[(2... 9 0
Renin inhibitor SureCN5073976 family 6 0
Renin inhibitor AGN-PC-00CP4L family 2 0
Renin inhibitor 3-(4-amino-4-oxobutanoyl)-N-[(2-chlorophenyl)m... 2 0
Renin inhibitor (1R,5S)-3-acetyl-7-[4-[3-(2-bromo-5-fluorophen... 3 0
Renin inhibitor (1R,5S)-N-[(2-chlorophenyl)methyl]-7-[4-[3-[(2... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00440729 CHEMBL510822 Bioactive (1R,5S)-3-acetyl-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-7-[4-[2-(2-methoxyphenoxy)ethoxy]phenyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440722 CHEMBL508205 Bioactive SureCN5073756
CFAMM00440728 CHEMBL449779 Bioactive (1R,5S)-3-acetyl-7-[4-[2-(3-chloro-2,6-difluorophenoxy)ethoxy]phenyl]-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440721 CHEMBL443718 Bioactive (1R,5S)-3-acetyl-N-cyclopropyl-7-[4-[2-(2,6-dichloro-4-fluorophenoxy)ethoxy]phenyl]-N-[(2,3-dichlorophenyl)methyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440727 CHEMBL503443 Bioactive (1R,5S)-3-acetyl-7-[4-[2-(2-chloro-3,6-difluorophenoxy)ethoxy]phenyl]-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440726 CHEMBL470878 Bioactive (1R,5S)-3-acetyl-7-[4-[2-(2-chlorophenoxy)ethoxy]phenyl]-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440725 CHEMBL475671 Bioactive (1R,5S)-3-acetyl-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-7-[4-[2-(2,3,6-trifluorophenoxy)ethoxy]phenyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440731 CHEMBL509242 Bioactive (1R,5S)-3-acetyl-7-[4-[2-(3-chlorophenoxy)ethoxy]phenyl]-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440724 CHEMBL506268 Bioactive (1R,5S)-3-acetyl-N-cyclopropyl-7-[4-[2-(2,6-dichloro-3,4-dimethylphenoxy)ethoxy]phenyl]-N-[(2,3-dichlorophenyl)methyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440730 CHEMBL447104 Bioactive (1R,5S)-3-acetyl-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-7-[4-(2-phenoxyethoxy)phenyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00440723 CHEMBL453778 Bioactive (1R,5S)-3-acetyl-7-[4-[2-(4-chlorophenoxy)ethoxy]phenyl]-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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