CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17142
Family Name Glycogen phosphorylase, liver form inhibitor SureCN5195475 family
No. of Seeds 9 No. of Other Members 5
Family Centroid CFAMM00440743 Functional Category Bioactive with Natural Product
Superfamily Granotapide Superfamily
Class Class 1380

Cousin Family NamesSeedsMembers
Thymidylate synthase Inhibitor Leucovorin/5-fluorouracil Family 9 83
Trifunctional purine biosynthetic protein adenosine-3 Inhibito... 2 1
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Substance-P receptor ligand (2S)-2-N-[(2S)-1-[benzyl(methyl)am... 3 3
C-C chemokine receptor type 2 ligand N-[2-[[(2S,3S)-1-[(2,4-di... 13 8
C-C chemokine receptor type 2 ligand N-[3-amino-5-(trifluorome... 4 1
Sphingosine 1-phosphate receptor 1 ligand 7-(2-hydroxyethyl)-1... 2 10
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(4... 5 1
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 5
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[4-[2-[... 1 0
Glycogen phosphorylase, liver form inhibitor SureCN5419308 family 3 0
Glycogen phosphorylase, liver form inhibitor AGN-PC-00CDLB family 2 0
Glutamate receptor ionotropic, kainate 1 and Glutamate recepto... 1 12


External ID

Functional Category

Molecule Name

CFAMM00440752 CHEMBL458655 Bioactive SureCN5192995
CFAMM00440745 CHEMBL459792 Bioactive (2S,3R)-2-[[2-[[4-(cyclopropylmethyl)-2,6-dimethylphenyl]carbamoylamino]-4-fluorobenzoyl]amino]-3-[(2-methylpropan-2-yl)oxy]butanoic acid
CFAMM00440744 CHEMBL443938 Bioactive SureCN5195733
CFAMM00440750 CHEMBL474193 Bioactive SureCN5196426
CFAMM00440743 CHEMBL472292 Bioactive SureCN5195475
CFAMM00440748 CHEMBL449986 Bioactive (2S,3R)-2-[[2-[(2,6-dimethyl-4-propylphenyl)carbamoylamino]-4-(3-fluorophenyl)benzoyl]amino]-3-[(2-methylpropan-2-yl)oxy]butanoic acid
CFAMM00440755 CHEMBL473486 Bioactive (2S,3R)-2-[[2-[(2,6-dimethyl-4-propylphenyl)carbamoylamino]-4-fluorobenzoyl]amino]-3-[(2-methylpropan-2-yl)oxy]butanoic acid
CFAMM00440746 CHEMBL471469 Bioactive SureCN5192546

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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