CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17152
Family Name Thromboxane-A synthase inhibitor AGN-PC-00NE8C family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00440797 Functional Category Bioactive
Superfamily Type-1B angiotensin II receptor and NS3 Binder Superfamily
Class Class 716

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1 angiotensin II receptor Ligand Eprosartan Family 36 176
Eluxadoline family 4 85
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-57893 Family 3 8
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Bombesin receptor subtype-3 ligand AGN-PC-07ZAKV family 13 23
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 7 11
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 7 3
Adenosine receptor A1 ligand AGN-PC-07PMLW family 6 4
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 9
Type-1A angiotensin II receptor ligand 2-[[2-butyl-3-[[4-[(2-c... 3 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 1
Dipeptidyl peptidase 4 inhibitor 3-[6-[(3R,4S)-3-amino-4-(2,4,... 3 7
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 3... 5 14
Platelet-activating factor receptor ligand SureCN7491834 family 28 15
Endothelin-1 receptor and Endothelin B receptor ligand SureCN9... 3 10
Scavenger receptor class B member 1 ligand methyl 9-[3-(4,6-di... 2 10
Neuropeptide Y receptor type 5 ligand SureCN4170426 family 4 13
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 3-methyl-4... 15 14
Lysine--tRNA ligase inhibitor 4-[[2-(2-piperazin-1-ylpyridin-4... 2 0
Type-1A angiotensin II receptor ligand 2-[[2-butyl-3-[(4-carbo... 2 4
C-C chemokine receptor type 5 ligand AC1MHRXO family 5 1
Type-1 angiotensin II receptor ligand 2-butyl-3-[[4-(2-carboxy... 1 7
Type-1 angiotensin II receptor ligand 2-propyl-3-[[4-[2-(2H-te... 3 0
Thromboxane A2 receptor and Thromboxane-A synthase ligand AGN-... 2 3
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 6
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 1 1
Cell division cycle 7-related protein kinase inhibitor Pyrrolo... 2 6
Adenosine receptor A2b and Adenosine receptor A1 ligand [4-(2,... 6 15
Neuropeptide Y receptor type 5 ligand AGN-PC-077LX1 family 8 1
Type-1 angiotensin II receptor ligand 2-ethyl-4-[[4-[2-(2H-tet... 2 0
Vascular endothelial growth factor receptor 2 and Vascular end... 1 0
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Lysosomal Pro-X carboxypeptidase inhibitor 9H-fluoren-9-ylmeth... 1 1
Type-1B angiotensin II receptor ligand SureCN9590246 family 1 6
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 1 0
Tyrosine-protein kinase JAK2 inhibitor SureCN2601181 family 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00440797 CHEMBL44445 Bioactive AGN-PC-00NE8C
CFAMM00440794 CHEMBL79242 Bioactive 4-[[2-butyl-5-[[[(1R)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]methyl]imidazol-1-yl]methyl]benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27406 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543