CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17161
Family Name Coagulation factor X inhibitor SureCN5641901 family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00440827 Functional Category Bioactive
Superfamily Coagulation factor X and Prothrombin Binder Superfamily 10
Class Class 3226

Cousin Family NamesSeedsMembers
Coagulation factor X Inhibitor Apixaban Family 34 52
Corticotropin-releasing factor receptor 1 Ligand GW876008 Family 3 30
DCC-2036 family 2 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 28
Adenosine receptor A3 ligand AGN-PC-07N4XZ family 4 11
Serine/threonine-protein kinase PLK1 and Serine/threonine-prot... 14 42
Adenosine receptor A3 ligand CHEMBL1834696 family 5 18
Cellular tumor antigen p53 inhibitor CHEMBL1401545 family 1 25
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 35
Thyroid hormone receptor beta and Cruzipain ligand CHEMBL14730... 1 12
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QJGR family 3 13
Coagulation factor X and Prothrombin inhibitor 6-[4-[2-[[(3R)-... 15 2
Serine/threonine-protein kinase PLK1 inhibitor AGN-PC-0A9RFQ f... 2 1
Tyrosine-protein kinase JAK2 inhibitor (2S)-1-[4-[4-[[7-(2-met... 11 27
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 12 13
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 10
Coagulation factor X and Prothrombin inhibitor 1-(4-methoxyphe... 8 0
Coagulation factor X inhibitor AGN-PC-046QD2 family 6 0
Coagulation factor X inhibitor SureCN6785555 family 7 0
Vascular endothelial growth factor receptor 2 and Serine/threo... 6 13
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
Mast/stem cell growth factor receptor Kit and Epithelial disco... 3 0
Adenosine receptor A2a and Cytochrome P450 3A4 ligand N-[6-(3,... 5 2
Hepatocyte growth factor receptor ligand AGN-PC-00AG7Q family 1 10
C-X-C chemokine receptor type 3 ligand N-[(1R)-1-[1-(4-ethoxyp... 5 9
Adenosine receptor A3 and Adenosine receptor A1 ligand N-[2-(4... 3 2
Coagulation factor X inhibitor AGN-PC-046RMQ family 1 0
Coagulation factor X inhibitor AGN-PC-077MYE family 16 0
Coagulation factor X inhibitor SureCN5644036 family 30 0
Coagulation factor X inhibitor AGN-PC-077MVW family 5 0
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 7 5
Coagulation factor X inhibitor SureCN5644554 family 2 0
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL4... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00440828 CHEMBL471550 Bioactive SureCN5644082
CFAMM00440827 CHEMBL458426 Bioactive SureCN5641901
CFAMM00440831 CHEMBL513062 Bioactive 1-(4-methoxyphenyl)-6-[4-[1-[(1,3-thiazol-2-ylamino)methyl]cyclopropyl]phenyl]-3-(trifluoromethyl)-4,5-dihydropyrazolo[3,4-c]pyridin-7-one
CFAMM00440830 CHEMBL445335 Bioactive AGN-PC-077MZR
CFAMM00440829 CHEMBL515066 Bioactive SureCN5643530

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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