CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17176
Family Name Gastrin/cholecystokinin type B receptor ligand AGN-PC-077L8M family
No. of Seeds 24 No. of Other Members 10
Family Centroid CFAMM00440914 Functional Category Bioactive
Superfamily Dihydrofolate reductase and Cholecystokinin receptor type A Binder Superfamily
Class Class 850

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Divapl... 3 47
Thromboxane A2 receptor ligand AC1NSKJR family 13 42
Melanocortin receptor 4 ligand AGN-PC-076AML family 3 24
NS5B protein inhibitor AC1LAMEZ family 1 18
Platelet-activating factor receptor ligand SureCN7497229 family 4 2
Cholecystokinin receptor type A ligand AGN-PC-0A9S2C family 4 8
Cholecystokinin receptor type A ligand AGN-PC-0A9ULH family 8 8
Cholecystokinin receptor type A ligand AGN-PC-0A9TYH family 1 0
NS5B protein inhibitor (2E)-1-cyclohexyl-2-(2-fluoro-4-oxocycl... 2 10
Elongation factor 1-alpha 1 and Elongation factor 1-alpha 2 in... 2 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 7
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 29
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 4-[4-[1-(6... 10 0
Coagulation factor X inhibitor AGN-PC-07C10A family 3 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 0
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 4 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN2... 1 2
NS5B protein and Genome polyprotein inhibitor AC1LAG00 family 1 19
Cannabinoid receptor 2 ligand AGN-PC-03LKW5 family 24 5
Cholecystokinin receptor type A ligand AGN-PC-077L8J family 22 2
Cholecystokinin receptor type A ligand SureCN3132309 family 11 0
Cholecystokinin receptor type A ligand AGN-PC-077KXF family 2 0


External ID

Functional Category

Molecule Name

CFAMM00440914 CHEMBL446789 Bioactive AGN-PC-077L8M
CFAMM00440922 CHEMBL448221 Bioactive AGN-PC-077L0R
CFAMM00440936 CHEMBL509519 Bioactive AGN-PC-04SSZO
CFAMM00440925 CHEMBL505409 Bioactive SureCN2204002
CFAMM00440915 CHEMBL510690 Bioactive 3-[4-[2-(2,4-difluorophenyl)-1-(3-ethoxyphenyl)imidazole-4-carbonyl]piperazin-1-yl]naphthalene-1-carboxylic acid
CFAMM00440913 CHEMBL504114 Bioactive SureCN2914922
CFAMM00440921 CHEMBL507094 Bioactive 3-[(3R)-4-[1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)imidazole-4-carbonyl]-3-[(methylcarbamoylamino)methyl]piperazin-1-yl]naphthalene-1-carboxylic acid
CFAMM00440935 CHEMBL505969 Bioactive AGN-PC-077L8N
CFAMM00440924 CHEMBL508772 Bioactive SureCN2915306
CFAMM00440934 CHEMBL502974 Bioactive 3-[(3S)-3-(acetamidomethyl)-4-[1-(3-ethoxyphenyl)-2-(4-methylphenyl)imidazole-4-carbonyl]piperazin-1-yl]naphthalene-1-carboxylic acid
CFAMM00440929 CHEMBL446324 Bioactive 3-[(3R)-4-[1-(3-ethoxyphenyl)-2-(4-methylphenyl)imidazole-4-carbonyl]-3-(methanesulfonamidomethyl)piperazin-1-yl]naphthalene-1-carboxylic acid
CFAMM00440919 CHEMBL451342 Bioactive 3-[(3S)-4-[1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)imidazole-4-carbonyl]-3-(methanesulfonamidomethyl)piperazin-1-yl]naphthalene-1-carboxylic acid
CFAMM00440933 CHEMBL498958 Bioactive 3-[(3S)-3-(carboxymethoxymethyl)-4-[1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)imidazole-4-carbonyl]piperazin-1-yl]naphthalene-1-carboxylic acid
CFAMM00440939 CHEMBL504861 Bioactive AGN-PC-04SSQF
CFAMM00440928 CHEMBL507051 Bioactive 3-[(3S)-4-[1-(3-ethoxyphenyl)-2-(4-methylphenyl)imidazole-4-carbonyl]-3-[(methylcarbamoylamino)methyl]piperazin-1-yl]naphthalene-1-carboxylic acid
CFAMM00440938 CHEMBL509464 Bioactive SureCN2915467
CFAMM00440927 CHEMBL503107 Bioactive 3-[(3R)-4-[1-(3-ethoxyphenyl)-2-(4-methylphenyl)imidazole-4-carbonyl]-3-(propan-2-ylcarbamoyl)piperazin-1-yl]naphthalene-1-carboxylic acid
CFAMM00440909 CHEMBL451644 Bioactive AGN-PC-04SSZM
CFAMM00440917 CHEMBL506201 Bioactive AGN-PC-077L8L
CFAMM00440937 CHEMBL455742 Bioactive AGN-PC-04SSTL
CFAMM00440926 CHEMBL505727 Bioactive SureCN502146
CFAMM00440908 CHEMBL498942 Bioactive AGN-PC-04SSRW
CFAMM00440932 CHEMBL505225 Bioactive AGN-PC-04SSZL
CFAMM00440916 CHEMBL504406 Bioactive SureCN2921194

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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