CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17190
Family Name Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-077PIN family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00441009 Functional Category Bioactive
Superfamily Cholinesterase and Acetylcholinesterase Binder Superfamily 13
Class Class 3040

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dibucaine F... 2 136
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Phospholipase A2 Inhibitor Quinacrine Family 13 95
Multidrug resistance protein Inhibitor Tariquidar Family 3 60
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Platelet-derived growth factor receptor alpha and Platelet-der... 2 17
Adenosine receptor A1 and Adenosine receptor A3 Ligand 4-metho... 1 16
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
Neuromedin-K receptor Ligand 3-methoxy-n',2-diphenylquinoline-... 14 33
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-methoxyphenyl)qu... 2 11
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 2 30
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 8 12
Acetylcholinesterase and Cholinesterase inhibitor (2Z)-5-metho... 4 23
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(1,3-... 2 9
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Vascular endothelial growth factor receptor 2 and Vascular end... 2 52
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Cholinesterase and Acetylcholinesterase inhibitor 4-oxo-N-[9-(... 11 13
Acetylcholinesterase and Cholinesterase inhibitor N-[10-[(6-ch... 6 0
Disintegrin and metalloproteinase domain-containing protein 17... 13 3
Disintegrin and metalloproteinase domain-containing protein 17... 16 2
Acetylcholinesterase and Butyrylcholinesterase inhibitor (E)-3... 4 5
Cholinesterase and Acetylcholinesterase inhibitor tacrine deri... 10 0
Cholinesterase and Acetylcholinesterase inhibitor 6-[2-methoxy... 12 6
Proto-oncogene tyrosine-protein kinase receptor Ret and Vascul... 5 14
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-073E7... 2 4
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-077PJ... 4 4
Inositol monophosphatase 1 and Prelamin-A/C inhibitor GNF-Pf-3... 1 5
Survival motor neuron protein and Arachidonate 15-lipoxygenase... 1 2
Signal transducer and activator of transcription 1-alpha/beta ... 1 36
Aurora kinase A inhibitor SureCN3802792 family 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00441009 CHEMBL502725 Bioactive AGN-PC-077PIN
CFAMM00441012 CHEMBL447544 Bioactive AGN-PC-077PIM

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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