CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17197
Family Name Macrophage colony-stimulating factor 1 receptor ligand AGN-PC-050GR1 family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00441028 Functional Category Bioactive
Superfamily Macrophage colony-stimulating factor 1 receptor and Serine/threonine-protein kinase mTOR Binder Superfamily
Class Class 1031

Cousin Family NamesSeedsMembers
Cyclin-dependent kinase 4 Inhibitor PD-332991 Family 13 155
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
JAK Inhibitor Momelotinib Family 33 83
XL-888 family 16 85
Cathepsin K and Cathepsin S inhibitor 2-Cyano-pyrimidine, 17d ... 5 9
Serine/threonine-protein kinase PLK2 and Serine/threonine-prot... 4 8
Macrophage colony-stimulating factor 1 receptor and Mast/stem ... 27 4
Macrophage colony-stimulating factor 1 receptor ligand AGN-PC-... 5 0


External ID

Functional Category

Molecule Name

CFAMM00441028 CHEMBL448339 Bioactive AGN-PC-050GR1
CFAMM00441027 CHEMBL450914 Bioactive AGN-PC-078WVS

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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