CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17209
Family Name Sodium-dependent serotonin transporter and Sodium-dependent noradrenaline transporter inhibitor AGN-PC-078ZGZ family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00150424 Functional Category Bioactive
Superfamily Alpha-2A adrenergic receptor and 5-hydroxytryptamine receptor 6 Binder Superfamily
Class Class 3409

Cousin Family NamesSeedsMembers
Mannose-6-phosphate isomerase Inhibitor Sulfoxone Family 3 20
5-hydroxytryptamine receptor Ligand Lu AA21004 Family 13 39
5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)pheny... 8 25
Sodium-dependent serotonin transporter and Sodium-dependent no... 6 1
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 8 10
Sodium-dependent serotonin transporter and Sodium-dependent do... 4 1
5-hydroxytryptamine receptor 6 ligand AGN-PC-075CMN family 2 1
Sodium-dependent serotonin transporter and Transporter inhibit... 4 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[[4... 7 11
5-hydroxytryptamine receptor 6 ligand AGN-PC-014RDG family 1 3
Carbonic anhydrase and Carbonic anhydrase 2 inhibitor AGN-PC-0... 2 0
Amine oxidase [flavin-containing] A inhibitor SureCN5111868 fa... 2 0


External ID

Functional Category

Molecule Name

CFAMM00441106 CHEMBL479411 Bioactive AGN-PC-078ZGY
CFAMM00441105 CHEMBL479783 Bioactive AGN-PC-078ZH0
CFAMM00441103 CHEMBL482295 Bioactive AGN-PC-078ZGC

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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