CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17226
Family Name Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-077PJ5 family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00086964 Functional Category Bioactive with Natural Product
Superfamily Cholinesterase and Acetylcholinesterase Binder Superfamily 13
Class Class 3040

Cousin Family NamesSeedsMembers
DNA Binder Primaquine Family 3 245
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Phospholipase A2 Inhibitor Quinacrine Family 13 95
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Nicotinic acetylcholine receptor alpha2 / alpha3 Ligand Ibogai... 3 21
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Oestrogen receptor and Estrogen receptor beta Ligand 4-(3-phen... 5 14
5-hydroxytryptamine receptor 2A and Alpha-2A adrenergic recept... 4 29
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 38 35
Melanin-concentrating hormone receptor 1 and Cytochrome P450 3... 8 2
Prelamin-A/C inhibitor 1-[(3,4-dimethoxyphenethyl)amino]-3-(1H... 1 2
Hypoxia-inducible factor 1-alpha and Lethal factor inhibitor C... 1 1
Butyrylcholinesterase and Acetylcholinesterase inhibitor AGN-P... 9 24
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 2 13
Somatostatin receptor type 2 ligand SureCN4313450 family 2 25
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-09Q7W... 7 3
Sodium-dependent serotonin transporter inhibitor SureCN7536104... 6 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 5
Acetylcholinesterase and Butyrylcholinesterase inhibitor (E)-3... 4 5
Cholinesterase and Acetylcholinesterase inhibitor tacrine deri... 10 0
Cholinesterase and Acetylcholinesterase inhibitor 6-[2-methoxy... 12 6
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 6 4
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 4 4
C5a anaphylatoxin chemotactic receptor 1 ligand 2-(2,6-diethyl... 3 5
D(1A) dopamine receptor and D(2) dopamine receptor ligand (6aR... 3 6
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 4
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-077PI... 4 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 23 5
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-04UHB... 4 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 18 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 1
Histidine-rich protein PFHRP-II inhibitor AGN-PC-075SYG family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00441216 CHEMBL486507 Bioactive AGN-PC-077PJ3
CFAMM00441215 CHEMBL486508 Bioactive AGN-PC-077PJ4

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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