CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17230
Family Name Vascular endothelial growth factor receptor 2 ligand AGN-PC-007LPL family
No. of Seeds 9 No. of Other Members 2
Family Centroid CFAMM00441228 Functional Category Bioactive
Superfamily Hepatocyte growth factor receptor and Vascular endothelial growth factor receptor 2 Binder Superfamily
Class Class 938

Cousin Family NamesSeedsMembers
DNA Binder Primaquine Family 3 245
Alpha-1D adrenergic receptor Ligand Terazosin Family 28 638
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
Multidrug resistance protein Inhibitor Tariquidar Family 3 60
Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
Aurora kinase B and Aurora kinase A Inhibitor AZD1152 Family 24 11
Vascular endothelial growth factor receptor 2 Ligand E 7080 Fa... 7 17
Tivozanib family 4 6
Platelet-derived growth factor receptor alpha and Platelet-der... 2 17
Platelet-derived growth factor receptor beta and Epidermal gro... 3 7
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 2 3
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 3
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 6 9
Equilibrative nucleoside transporter 1 inhibitor SureCN9046933... 2 9
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 2
Vascular endothelial growth factor receptor 3 and Platelet-der... 8 13
Platelet-derived growth factor receptor beta and Receptor-type... 6 5
Platelet-derived growth factor receptor beta and Receptor-type... 5 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 3
Macrophage colony-stimulating factor 1 receptor and Ephrin typ... 1 0
Platelet-derived growth factor receptor beta and Macrophage co... 8 0
Platelet-derived growth factor receptor beta and Macrophage co... 7 0
Platelet-derived growth factor receptor beta and Macrophage co... 1 4
Platelet-derived growth factor receptor alpha and Mast/stem ce... 2 2
Hepatocyte growth factor receptor and Vascular endothelial gro... 14 10
Protein-tyrosine kinase 2-beta and Focal adhesion kinase 1 inh... 3 6
Hepatocyte growth factor receptor and Vascular endothelial gro... 15 0
Vascular endothelial growth factor receptor 2 and Aurora kinas... 4 3
Tubulin beta-4A chain and Tubulin beta-2B chain inhibitor N-(2... 1 4
Adenosine receptor A2a and Cytochrome P450 3A4 ligand N-[6-(3,... 5 2
Hepatocyte growth factor receptor ligand 1-(2-chlorophenyl)-N-... 14 8
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 11 7
Serine/threonine-protein kinase Chk1 inhibitor SureCN4854955 f... 2 0
Vascular endothelial growth factor receptor 2 ligand 6-(6,7-di... 4 0
Vascular endothelial growth factor receptor 2 and Cytochrome P... 2 1
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 4 4
Adenosine receptor A3 and Adenosine receptor A1 ligand N-[2-(4... 3 2
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 1 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 4 0
Tyrosine-protein kinase Lck inhibitor AGN-PC-07R5ZB family 4 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D inhibitor Sure... 2 6
Tubulin beta-4A chain and Tubulin beta-2B chain inhibitor AGN-... 3 15
Vascular endothelial growth factor receptor 2 and Vascular end... 8 1
Glucokinase inhibitor 3-[(E)-2-(2-fluorophenyl)ethenyl]-5-[(2S... 1 15
Vascular endothelial growth factor receptor 2 and Vascular end... 1 0
Serine/threonine-protein kinase PLK1 inhibitor SureCN3992071 f... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00441230 CHEMBL462562 Bioactive SureCN4376686
CFAMM00441236 CHEMBL462175 Bioactive SureCN4373538
CFAMM00441235 CHEMBL450163 Bioactive AGN-PC-0098RQ
CFAMM00441228 CHEMBL518203 Bioactive AGN-PC-007LPL
CFAMM00441234 CHEMBL462003 Bioactive AGN-PC-008JES
CFAMM00441233 CHEMBL462349 Bioactive AGN-PC-009OHK
CFAMM00441232 CHEMBL462348 Bioactive AGN-PC-007LZE
CFAMM00441231 CHEMBL462563 Bioactive SureCN4370347

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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