CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17232
Family Name Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-04X9O4 family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00441245 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and Prelamin-A/C Binder Superfamily
Class Class 216

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Caspase-3 Inhibitor 2-(4-methoxy-benzyl)isoquinoline-1,3,4-tri... 2 2
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Acetylcholinesterase and Cholinesterase Inhibitor Caproctamine... 7 17
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 2
Peroxisome proliferator-activated receptor delta and Peroxisom... 20 8
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 2 0
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 1 1
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745OX family 2 0
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 10 8
Leukotriene B4 receptor 1 ligand AGN-PC-00GEAR family 2 2
Multidrug resistance protein 1 inhibitor 1-[2-[(2R)-3-[4-(2,3-... 2 41
Substance-P receptor ligand AGN-PC-075NP5 family 4 8
Prelamin-A/C and Retinal dehydrogenase 1 inhibitor CHEMBL15810... 1 1
Pol polyprotein inhibitor CHEMBL305466 family 4 7
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 15 4
Estrogen receptor and Estrogen receptor beta ligand SureCN1450... 1 1
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 15
Free fatty acid receptor 1 ligand (3R,4R)-3-[4-(3,4-dimethylph... 4 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00441246 CHEMBL507903 Bioactive 2,6-bis[6-[ethyl-[(2-methoxyphenyl)methyl]amino]hexyl]pyrrolo[3,4-f]isoindole-1,3,5,7-tetrone
CFAMM00441245 CHEMBL450553 Bioactive AGN-PC-04X9O4

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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