CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17237
Family Name Coagulation factor X and Tissue factor inhibitor AGN-PC-02WN8Y family
No. of Seeds 7 No. of Other Members 22
Family Centroid CFAMM00441284 Functional Category Bioactive
Superfamily Tissue factor and Plasminogen Binder Superfamily
Class Class 2096

Cousin Family NamesSeedsMembers
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Cholecystokinin receptor type A Ligand Gi 181771 Family 3 18
Histone deacetylase 1 and Tyrosine-protein kinase JAK2 Inhibit... 2 3
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzyl... 2 19
Integrin alpha-2 and Integrin beta-3 Inhibitor 3-(3-(carbamoyl... 7 13
Beta-secretase 1 Inhibitor KMI-538 Family 4 20
Integrin beta-3 and Integrin alpha-IIb inhibitor 2-[7-[[4-(N'-... 7 15
Tissue factor and Plasminogen inhibitor AGN-PC-077TVT family 3 6
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7345980... 4 6
Stromelysin-1 inhibitor 6-(4'-FLUORO-BIPHENYL-4-YL)-4-(3-METHY... 3 0
Bifunctional epoxide hydrolase 2 inhibitor 6-[[1-(2,4-dimethyl... 1 3
Coagulation factor VII inhibitor 2-[2-[(1-aminoisoquinolin-6-y... 1 14
Dihydrofolate reductase inhibitor AGN-PC-073POJ family 1 0
Beta-3 adrenergic receptor ligand SureCN5704018 family 4 1
Mitogen-activated protein kinase 14 inhibitor SureCN4822166 fa... 1 4
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-0BOW0P... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[[1... 2 5
Protein farnesyltransferase subunit beta and Protein farnesylt... 2 4


External ID

Functional Category

Molecule Name

CFAMM00441284 CHEMBL507020 Bioactive AGN-PC-02WN8Y
CFAMM00441270 CHEMBL505189 Bioactive SureCN3812577
CFAMM00441287 CHEMBL505190 Bioactive SureCN3813137
CFAMM00441267 CHEMBL451066 Bioactive AGN-PC-077TXF
CFAMM00441280 CHEMBL502293 Bioactive AGN-PC-077TXD
CFAMM00441293 CHEMBL486112 Bioactive AGN-PC-077U0Y
CFAMM00441266 CHEMBL485704 Bioactive SureCN3818101

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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