CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17246
Family Name Substance-P receptor ligand N-[(3S,5S)-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-2-oxo-5-phenylpyrrolidin-3-yl]propanamide family
No. of Seeds 10 No. of Other Members 0
Family Centroid CFAMM00441342 Functional Category Bioactive
Superfamily Substance-P receptor and Lethal factor Binder Superfamily
Class Class 3563

Cousin Family NamesSeedsMembers
Substance-P receptor Ligand L-733060 Family 19 71
Substance-P receptor Ligand SCH-388714 Family 26 8
Substance-P receptor ligand 1-[(1R,2S,3S)-3-[[3,5-bis(trifluor... 7 2
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 5 1
Substance-P receptor ligand 1-[(3S,4R)-3-[(1R)-1-[3,5-bis(trif... 9 0
Substance-P receptor ligand (5S)-5-[(3S,4R)-3-[(1R)-1-[3,5-bis... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00441338 CHEMBL451763 Bioactive N-[(3S,5S)-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-2-oxo-5-phenylpyrrolidin-3-yl]methanesulfonamide
CFAMM00441337 CHEMBL452532 Bioactive N-[(3R,5S)-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-2-oxo-5-phenylpyrrolidin-3-yl]propanamide
CFAMM00441343 CHEMBL460890 Bioactive (3S,5S)-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-5-phenyl-3-pyrrolidin-1-ylpyrrolidin-2-one
CFAMM00441336 CHEMBL452270 Bioactive N-[(3S,5S)-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-2-oxo-5-phenylpyrrolidin-3-yl]acetamide
CFAMM00441342 CHEMBL451765 Bioactive N-[(3S,5S)-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-2-oxo-5-phenylpyrrolidin-3-yl]propanamide
CFAMM00441335 CHEMBL452271 Bioactive N-[(3R,5S)-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-2-oxo-5-phenylpyrrolidin-3-yl]acetamide
CFAMM00441341 CHEMBL451764 Bioactive N-[(3R,5S)-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-2-oxo-5-phenylpyrrolidin-3-yl]methanesulfonamide
CFAMM00441334 CHEMBL517121 Bioactive (5S)-3-amino-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-5-phenylpyrrolidin-2-one
CFAMM00441340 CHEMBL453055 Bioactive (3R,5S)-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-3-(2-oxopyrrolidin-1-yl)-5-phenylpyrrolidin-2-one
CFAMM00441339 CHEMBL453054 Bioactive (3S,5S)-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-3-(2-oxopyrrolidin-1-yl)-5-phenylpyrrolidin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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