CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17252
Family Name Beta-3 adrenergic receptor and Beta-1 adrenergic receptor ligand 4-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-N-methylsulfonyl-2-pentoxybenzamide;hydrochloride family
No. of Seeds 16 No. of Other Members 2
Family Centroid CFAMM00111954 Functional Category Bioactive
Superfamily Pol polyprotein and Beta-1 adrenergic receptor Binder Superfamily
Class Class 322

Cousin Family NamesSeedsMembers
Alpha-1 adrenergic receptor ligand arylethanolamine derivative... 4 37
Beta-2 adrenergic receptor Ligand Salmeterol Xinafoate Family 9 51
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Peroxisome proliferator-activated receptor delta and Peroxisom... 20 8
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 2 18
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 0
C-C chemokine receptor type 1 and Chemokine (C-C motif) recept... 1 16
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 14 1
Pol polyprotein inhibitor (3S)-N-tert-butyl-2-[(2R)-2-[(3S,6S,... 3 1
Beta-3 adrenergic receptor ligand 4-[4-[2-[[(2R)-2-(4-aminophe... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00441363 CHEMBL556852 Bioactive 4-[4-[2-[[(2R)-2-(4-aminophenyl)-2-hydroxyethyl]amino]ethyl]phenyl]-2-cyclohexyloxy-N-methylsulfonylbenzamide
CFAMM00441369 CHEMBL552012 Bioactive 4-[4-[2-[[(2R)-2-(3-aminophenyl)-2-hydroxyethyl]amino]ethyl]phenyl]-2-cyclohexyloxy-N-methylsulfonylbenzamide
CFAMM00441368 CHEMBL559486 Bioactive 2-cyclohexyloxy-4-[4-[(2S)-3-hydroxy-2-[[(2R)-2-hydroxy-2-phenylethyl]amino]propyl]phenyl]-N-methylsulfonylbenzamide
CFAMM00441374 CHEMBL562395 Bioactive 4-[4-[2-[[(2R)-2-(3-aminophenyl)-2-hydroxyethyl]amino]ethyl]phenyl]-N-methylsulfonyl-2-propan-2-yloxybenzamide
CFAMM00441367 CHEMBL561335 Bioactive 4-[4-[2-[[(2R)-2-(4-aminophenyl)-2-hydroxyethyl]amino]ethyl]phenyl]-N-methylsulfonyl-2-propan-2-yloxybenzamide
CFAMM00441372 CHEMBL492401 Bioactive SureCN4585694
CFAMM00441365 CHEMBL452134 Bioactive SureCN4586475
CFAMM00441371 CHEMBL469396 Bioactive SureCN4585980
CFAMM00441364 CHEMBL515397 Bioactive SureCN1622807
CFAMM00441370 CHEMBL469395 Bioactive SureCN4583890

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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