CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1727
Family Name Inosine-5'-monophosphate dehydrogenase inhibitor 1-[2-[3-[(E)-N-hydroxy-C-methylcarbonimidoyl]phenyl]propan-2-yl]-3-naphthalen-2-ylurea family
No. of Seeds 3 No. of Other Members 6
Family Centroid CFAMM00326843 Functional Category Bioactive
Superfamily Cannabinoid receptor 2 and Cannabinoid receptor 1 Binder Superfamily 10
Class Class 3438

Cousin Family NamesSeedsMembers
Sodium channel Ligand iminostilbene derivative (tricyclic stru... 2 46
NMDA receptor Ligand Aptiganel Hcl Family 2 82
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 7 134
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
DNA topoisomerase Inhibitor 6-(naphthalen-2-ylamino)-1h-pyrimi... 2 1
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 1-(3,5... 2 0
Fatty-acid amide hydrolase 1 inhibitor [(E)-1-[3-(3-carbamoylp... 1 0
Coagulation factor VII and Prothrombin inhibitor 2-[(4-carbami... 2 1


External ID

Functional Category

Molecule Name

CFAMM00326845 CHEMBL1210041 Bioactive [(E)-1-(3-phenylphenyl)ethylideneamino] N-naphthalen-1-ylcarbamate
CFAMM00326837 CHEMBL2178622 Bioactive 1-[2-[3-[(E)-N-methoxy-C-methylcarbonimidoyl]phenyl]propan-2-yl]-3-naphthalen-2-ylurea
CFAMM00326843 CHEMBL2178618 Bioactive 1-[2-[3-[(E)-N-hydroxy-C-methylcarbonimidoyl]phenyl]propan-2-yl]-3-naphthalen-2-ylurea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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