CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17272
Family Name Histamine H3 receptor and Potassium voltage-gated channel subfamily H member 2 ligand AGN-PC-00CROF family
No. of Seeds 16 No. of Other Members 2
Family Centroid CFAMM00441557 Functional Category Bioactive with Natural Product
Superfamily Histamine H3 receptor and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily 4
Class Class 3845

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Extracellular calcium-sensing receptor Ligand 2-furan-2-yl-3-p... 4 119
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-methoxy-phenyl)-... 1 3
Poly [ADP-ribose] polymerase 1 Inhibitor 8-methoxy-2-phenyl-3h... 4 6
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 28 91
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Prelamin-A/C and Survival motor neuron protein inhibitor CHEMB... 1 7
Vasopressin V1b receptor ligand AGN-PC-09QGT9 family 4 123
Vasopressin V1b receptor ligand AGN-PC-00HJ2S family 4 6
Growth hormone secretagogue receptor type 1 ligand (2R)-N-(1-b... 11 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 2
Dipeptidyl peptidase 4 and Cytochrome P450 3A4 inhibitor SureC... 2 3
C-X-C chemokine receptor type 3 ligand N-(2-ethoxyethyl)-N-[(1... 1 1
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 10
Ghrelin/growth hormone secretagogue receptor and Cytochrome P4... 5 20
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 9 18
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Histamine H3 receptor ligand AGN-PC-03Z8FM family 5 0
Histamine H3 receptor ligand AGN-PC-00AE5Q family 13 13
Histamine H3 receptor and Potassium voltage-gated channel subf... 28 30
Histamine H3 receptor ligand AGN-PC-03Z8HJ family 4 1
5-hydroxytryptamine receptor 7 ligand 4-[4-(2-ethoxyphenyl)pip... 2 5
Multidrug resistance protein 1B and Multidrug resistance-assoc... 1 4
Adenosine receptor A2a and Amine oxidase [flavin-containing] B... 4 0
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 3 0
NP (s)-2-(2-(6,7-dimethoxy-4-oxoquinazolin-3(4h)-yl)acetamido)... 10 1
NP 2-((8-allyl-9-oxo-1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoli... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00441565 CHEMBL519067 Bioactive AGN-PC-00E6SN
CFAMM00441556 CHEMBL453893 Bioactive AGN-PC-00CS6D
CFAMM00441555 CHEMBL453892 Bioactive AGN-PC-00APOF
CFAMM00441563 CHEMBL454879 Bioactive AGN-PC-00BR5M
CFAMM00441554 CHEMBL487230 Bioactive AGN-PC-00AEFG
CFAMM00441562 CHEMBL454642 Bioactive AGN-PC-00AEGG
CFAMM00441553 CHEMBL453653 Bioactive AGN-PC-00APOG
CFAMM00441552 CHEMBL488251 Bioactive AGN-PC-00DRUB
CFAMM00441568 CHEMBL487064 Bioactive AGN-PC-00AOYT
CFAMM00441559 CHEMBL455681 Bioactive AGN-PC-00BQW7
CFAMM00441567 CHEMBL453654 Bioactive AGN-PC-00AENG
CFAMM00441551 CHEMBL508712 Bioactive AGN-PC-00AUTF
CFAMM00441557 CHEMBL488249 Bioactive AGN-PC-00CROF

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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