CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17284
Family Name Epidermal growth factor receptor ligand (E)-1-[4-(3-bromoanilino)quinazolin-6-yl]hex-3-ene-2,5-dione family
No. of Seeds 9 No. of Other Members 0
Family Centroid CFAMM00441634 Functional Category Bioactive
Superfamily Epidermal growth factor receptor and Neuropeptide S receptor Binder Superfamily
Class Class 1053

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
JAK Inhibitor Momelotinib Family 33 83
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
Epidermal growth factor receptor and Receptor tyrosine-protein... 11 138
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Epidermal growth factor receptor Ligand N*4*-(3-bromo-phenyl)-... 7 11
Epidermal growth factor receptor Ligand Benzo[g]quinazolin-4-y... 5 3
Epidermal growth factor receptor Ligand (3-bromo-phenyl)-quina... 7 5
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Adenosine receptor A3 Ligand 1-(2-(diethylamino)quinazolin-4-y... 2 9
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 4 6
Glycogen synthase kinase-3 beta Inhibitor 4-(5-bromo-1h-indol-... 7 18
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Adenosine kinase inhibitor abt-702 family 14 1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 1 3
Epidermal growth factor receptor ligand AGN-PC-07Q1HU family 4 17
Adenosine kinase inhibitor 5-[3-(3-bromophenyl)propyl]-6-[2-(6... 3 0
Cathepsin K and Potassium voltage-gated channel subfamily H me... 4 7
Epidermal growth factor receptor ligand pyrido[4,3-d]pyrimidin... 11 0
Epidermal growth factor receptor ligand N-[4-(3-chloro-4-fluor... 8 4
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 2
Dihydrofolate reductase inhibitor 1-[3-(2,4-diaminoquinazolin-... 2 4
Heat shock protein HSP 90-beta inhibitor 1-(2-amino-4-methylqu... 1 2
Epidermal growth factor receptor ligand (2R,3R)-3-[[4-(3-bromo... 3 0
Substance-P receptor ligand 2-[3,5-bis(trifluoromethyl)phenyl]... 3 1
Tyrosine-protein kinase Lck and Vascular endothelial growth fa... 3 0
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... 11 2
Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-[6-(3-methy... 2 5
Adenosine kinase inhibitor 5-(4-bromophenyl)-6-[2-[4-(dimethyl... 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 4-[4... 1 1
Epidermal growth factor receptor ligand Pyrroloquinazoline der... 7 0
Epidermal growth factor receptor ligand AGN-PC-078X7L family 4 0
Epidermal growth factor receptor ligand (E)-N-[4-(3-bromoanili... 2 1
Epidermal growth factor receptor ligand N-[4-(3-bromoanilino)-... 2 0
Epidermal growth factor receptor ligand AGN-PC-073LJS family 4 0
Epidermal growth factor receptor ligand 4-Anilinopyrido[3,4-d]... 2 0
Epidermal growth factor receptor ligand (E)-5-[4-(3-bromoanili... 11 0
Epidermal growth factor receptor ligand AGN-PC-078X9P family 4 0
Transient receptor potential cation channel subfamily V member... 3 2
Mast/stem cell growth factor receptor Kit and Tyrosine-protein... 4 1
Dihydrofolate reductase inhibitor N-(2,4-diamino-5-methylquina... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00441633 CHEMBL517127 Bioactive AGN-PC-078X3A
CFAMM00441639 CHEMBL524132 Bioactive AGN-PC-078X0R
CFAMM00441632 CHEMBL507827 Bioactive (E)-1-[4-(3-bromoanilino)quinazolin-6-yl]-5,5,5-trifluoropent-3-en-2-one
CFAMM00441638 CHEMBL491085 Bioactive (E)-1-[4-(3-bromoanilino)quinazolin-6-yl]pent-3-en-2-one
CFAMM00441631 CHEMBL510396 Bioactive (E)-5-[4-(3-bromoanilino)quinazolin-6-yl]-4-oxopent-2-enoic acid
CFAMM00441637 CHEMBL461797 Bioactive (E)-5-[4-(3-bromoanilino)quinazolin-6-yl]-N-[3-(dimethylamino)propyl]-4-oxopent-2-enamide
CFAMM00441636 CHEMBL454384 Bioactive ethyl (E)-5-[4-(3-bromoanilino)quinazolin-6-yl]-4-oxopent-2-enoate
CFAMM00441635 CHEMBL461796 Bioactive 3-(dimethylamino)propyl (E)-5-[4-(3-bromoanilino)quinazolin-6-yl]-4-oxopent-2-enoate
CFAMM00441634 CHEMBL455174 Bioactive (E)-1-[4-(3-bromoanilino)quinazolin-6-yl]hex-3-ene-2,5-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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