CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17296
Family Name Melanocortin receptor 4 ligand 2-amino-N-[(2R)-3-(2,4-dichlorophenyl)-1-[4-[2-[(1R)-1-hydroxy-3-methylbutyl]phenyl]piperazin-1-yl]-1-oxopropan-2-yl]acetamide family
No. of Seeds 5 No. of Other Members 5
Family Centroid CFAMM00441690 Functional Category Bioactive
Superfamily Melanocortin receptor 4 and C-C chemokine receptor type 1 Binder Superfamily
Class Class 703

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
E3 ubiquitin-protein ligase Mdm2 inhibitor (2'R,3R,3'S,5'S)-6-... 17 51
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 15 12
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Squalene synthase inhibitor AGN-PC-09M2X2 family 12 22
Melanocortin receptor 4 ligand (3R)-N-[(2R)-3-(4-chlorophenyl)... 6 9
Melanocortin receptor 4 and Melanocortin receptor 5 ligand 3-[... 18 26
Melanocortin receptor 4 ligand 3-amino-N-[(2R)-3-(2,4-dichloro... 1 9
Melanocortin receptor 4 ligand SureCN6183720 family 2 5
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Growth hormone secretagogue receptor type 1 ligand N-[4,6-dich... 2 0
Renin inhibitor (E)-but-2-enedioic acid;(3S,5R)-5-[4-(2-chloro... 14 5
P2X purinoceptor 7 inhibitor AGN-PC-088GOO family 3 0
P2X purinoceptor 7 inhibitor SureCN3721807 family 3 0
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(3S,4R)-4-(4-c... 26 13
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 1 1
Nociceptin receptor and Delta-type opioid receptor ligand spir... 25 9
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
Glutamate receptor ionotropic, NMDA 2B and Potassium voltage-g... 4 9
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 7 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00441690 CHEMBL454906 Bioactive 2-amino-N-[(2R)-3-(2,4-dichlorophenyl)-1-[4-[2-[(1R)-1-hydroxy-3-methylbutyl]phenyl]piperazin-1-yl]-1-oxopropan-2-yl]acetamide
CFAMM00441689 CHEMBL471340 Bioactive N-[(2R)-3-(2,4-dichlorophenyl)-1-[4-[2-(1-hydroxy-3-methylbutyl)phenyl]piperazin-1-yl]-1-oxopropan-2-yl]-2-(methylamino)acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27265 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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