CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17307
Family Name Glucocorticoid receptor ligand 5-amino-N-[(2R)-2-[[(2,6-dichlorobenzoyl)-ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)pyrazole-4-carboxamide family
No. of Seeds 6 No. of Other Members 5
Family Centroid CFAMM00441745 Functional Category Bioactive
Superfamily Glucocorticoid receptor and Glucagon receptor Binder Superfamily
Class Class 1185

Cousin Family NamesSeedsMembers
Metabotropic glutamate receptor 5 Ligand N-(1,4-diphenyl-1h-py... 3 35
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07ZYJE fa... 15 5
Mitogen-activated protein kinase 14 inhibitor SureCN3632376 fa... 10 5
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07C64P fa... 8 4
Mitogen-activated protein kinase 13 inhibitor N-cyclopropyl-3-... 16 40
Mitogen-activated protein kinase 14 inhibitor 3ocg family 6 0
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 10
Mitogen-activated protein kinase kinase kinase kinase 5 and Du... 1 18
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M6OU fa... 8 7
Mitogen-activated protein kinase 14 inhibitor AGN-PC-069K8I fa... 12 3
Glucocorticoid receptor ligand N-ethyl-2-fluoro-N-[3,3,3-trifl... 16 7
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 13 3
Mitogen-activated protein kinase 14 inhibitor ethyl N-[4-[5-(m... 5 2
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 6 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor AGN-... 1 1
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Glucocorticoid receptor ligand 5-amino-N-[2-[(1-ethyl-3,4-dihy... 1 0
Glucocorticoid receptor ligand N-[2-[[[5-amino-1-(4-fluorophen... 1 0
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-04VNKY family 1 4
Mitogen-activated protein kinase 14 inhibitor AGN-PC-00CRQ3 fa... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00441740 CHEMBL467633 Bioactive AGN-PC-04RRME
CFAMM00441745 CHEMBL455662 Bioactive 5-amino-N-[(2R)-2-[[(2,6-dichlorobenzoyl)-ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)pyrazole-4-carboxamide
CFAMM00441737 CHEMBL517440 Bioactive AGN-PC-04UQCB
CFAMM00441743 CHEMBL518451 Bioactive 5-amino-N-[2-[[ethyl-(2,4,6-trichlorobenzoyl)amino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)pyrazole-4-carboxamide
CFAMM00441741 CHEMBL520750 Bioactive 5-amino-N-[2-[[(2-chloro-3-fluorobenzoyl)-ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)pyrazole-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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