CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17308
Family Name C-C chemokine receptor type 2 and Cytochrome P450 2D6 ligand (E)-3-(3,5-difluorophenyl)-1-[4-[(1S)-2-hydroxy-1-[4-(1H-pyrrolo[2,3-b]pyridin-3-yl)piperidin-1-yl]ethyl]piperidin-1-yl]prop-2-en-1-one family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00441751 Functional Category Bioactive
Superfamily RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Superfamily
Class Class 1234

Cousin Family NamesSeedsMembers
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Adenosine receptor A1 and Adenosine receptor A2a Ligand OSIP-3... 4 31
Prothrombin inhibitor SureCN5856722 family 3 16
RAC-alpha serine/threonine-protein kinase and Proline-rich AKT... 2 4
C-C chemokine receptor type 2 ligand (E)-3-(3,4-dichlorophenyl... 3 2
LIM domain kinase 2 inhibitor 3-[[(cyanoamino)-[(2S)-2-methyl-... 6 0


External ID

Functional Category

Molecule Name

CFAMM00441748 CHEMBL487238 Bioactive SureCN5946961
CFAMM00441747 CHEMBL508073 Bioactive SureCN5947354
CFAMM00441751 CHEMBL455683 Bioactive (E)-3-(3,5-difluorophenyl)-1-[4-[(1S)-2-hydroxy-1-[4-(1H-pyrrolo[2,3-b]pyridin-3-yl)piperidin-1-yl]ethyl]piperidin-1-yl]prop-2-en-1-one
CFAMM00441750 CHEMBL508015 Bioactive SureCN5947353

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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