CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17319
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4A and Potassium voltage-gated channel subfamily H member 2 ligand AGN-PC-00KCW2 family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00441815 Functional Category Bioactive
Superfamily Nonstructural protein 1 and Serine-protein kinase ATM Binder Superfamily 3
Class Class 1374

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
SUR2-type K(ATP) channel Ligand Nicorandil Family 5 85
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Mitogen-activated protein kinase 12 Inhibitor VX-702 Family 3 49
Mast/stem cell growth factor receptor Kit and Vascular endothe... 4 47
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
XL-888 family 16 85
Class II cytokine receptor Ligand IL-10 Family 7 45
Tubulin beta chain Inhibitor 7-methyl-2-m-tolyl-1h-[1,8]naphth... 7 15
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Cyclin-dependent kinase 4 Inhibitor 1-(9-oxo-9h-fluoren-4-yl)-... 3 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Transient receptor potential cation channel subfamily V member... 6 23
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 4 6
Hydroxycarboxylic acid receptor 2 Ligand 2-(6-phenylhexyl)pyri... 4 11
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Reverse transcriptase Inhibitor PT-113 Family 3 4
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Metabotropic glutamate receptor 5 Ligand 3-cyano-5-fluoro-n-(p... 2 9
Tubulin beta chain Inhibitor 2-m-tolyl-1h-[1,8]naphthyridin-4-... 5 2
Tyrosine-protein kinase JAK2 and Potassium voltage-gated chann... 2 7
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 13 3
MAP kinase-activated protein kinase 2 inhibitor 4-fluoro-N-[4-... 25 1
Mast/stem cell growth factor receptor Kit and Mitogen-activate... 4 2
Protein kinase C theta type inhibitor (2-aminopyridin-3-yl)-[6... 4 1
Poly [ADP-ribose] polymerase 1 inhibitor 8-[[4-fluoro-3-(4-pyr... 5 2
Aurora kinase A and Aurora kinase B inhibitor 4-fluoro-N-[4-[(... 6 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor 6-... 1 0
Macrophage colony-stimulating factor 1 receptor and Mast/stem ... 27 4
Coagulation factor X inhibitor 5-bromo-N-(5-chloropyridin-2-yl... 1 1
Vasopressin V2 receptor and Vasopressin V1a receptor ligand Su... 2 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 7 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and Potassium ... 2 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and Potassium ... 2 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 1 0
Reverse transcriptase/RNaseH inhibitor PETT deriv. 13 family 1 0
Cannabinoid receptor 2 ligand AGN-PC-00SRU5 family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00441815 CHEMBL456172 Bioactive AGN-PC-00KCW2
CFAMM00441811 CHEMBL464600 Bioactive AGN-PC-077REG

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26241 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543