CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17323
Family Name High affinity nerve growth factor receptor ligand SureCN3337098 family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00441844 Functional Category Bioactive
Superfamily Aurora kinase A and Tyrosine-protein kinase Yes Binder Superfamily
Class Class 4596

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Xanthine dehydrogenase/oxidase Inhibitor 3,5-di(pyridin-4-yl)-... 6 3
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 3 12
Polycystin-2 and Serine/threonine-protein kinase D1 inhibitor ... 4 12
Aurora kinase A and Aurora kinase B inhibitor 3uol family 6 5
G1/S-specific cyclin-E1 and Cyclin-dependent kinase 2 inhibito... 1 5
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 3 11
Prothrombin and Survival motor neuron protein inhibitor CHEMBL... 2 14
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Tyrosine-protein kinase JAK2 inhibitor SureCN217071 family 1 0
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 9 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 4
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 9 2
BDNF/NT-3 growth factors receptor and NT-3 growth factor recep... 3 4
Mitogen-activated protein kinase 14 inhibitor imidazole 81 family 2 1
Casein kinase II subunit alpha inhibitor 2pvj family 3 1
Protein kinase C theta type and Protein kinase C delta type in... 9 0
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 6 0
High affinity nerve growth factor receptor ligand SureCN334011... 2 1
High affinity nerve growth factor receptor ligand SureCN490352... 3 0


External ID

Functional Category

Molecule Name

CFAMM00441844 CHEMBL456322 Bioactive SureCN3337098
CFAMM00441843 CHEMBL514257 Bioactive SureCN3341202
CFAMM00441846 CHEMBL456801 Bioactive SureCN4076742
CFAMM00441845 CHEMBL456802 Bioactive SureCN4068043

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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