CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1733
Family Name Beta-secretase 1 and Beta-secretase 2 inhibitor SureCN5224847 family
No. of Seeds 3 No. of Other Members 24
Family Centroid CFAMM00326877 Functional Category Bioactive
Superfamily Beta-secretase 1 and Beta-secretase 2 Binder Superfamily
Class Class 3128

Cousin Family NamesSeedsMembers
Beta-secretase 1 and Cathepsin D Inhibitor GRL-7234 Family 17 148
Beta-3 adrenergic receptor Ligand BMS-196085 Family 18 72
Beta-secretase 1 Inhibitor GSK-188909 Family 16 11
Beta-secretase 1 and Cathepsin D inhibitor 3ixk family 2 9
Beta-secretase 1 and Cathepsin D inhibitor 3ixj family 10 21
Beta-secretase 1 inhibitor SureCN3599637 family 1 0
Cathepsin S and Cathepsin L1 inhibitor arylaminoethyl amide, 8... 4 15
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Pol polyprotein inhibitor AC1LA9K7 family 7 23
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Beta-secretase 1 and Beta-secretase 2 inhibitor 3-(1,1-dioxoth... 6 2
Beta-secretase 1 inhibitor N-[(2S,3R)-1-(3,5-difluorophenyl)-3... 5 5
Beta-secretase 1 inhibitor 1-N-[(2S,3R)-1-(3,5-difluorophenyl)... 8 7
Cathepsin E and Cathepsin D inhibitor SureCN2529506 family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00326878 CHEMBL409752 Bioactive SureCN5223544
CFAMM00326877 CHEMBL253867 Bioactive SureCN5224847

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27746 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543