CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17330
Family Name Prostaglandin E2 receptor EP1 subtype ligand 3-acetamido-5-[2-(5-chloro-2-phenylmethoxyphenyl)phenyl]benzoic acid family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00441882 Functional Category Bioactive
Superfamily Pol polyprotein and Glucagon receptor Binder Superfamily
Class Class 281

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Tranilast Family 5 125
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
Metabotropic glutamate receptor 5 Ligand N-(3-(3-cyanobenzamid... 2 13
G-protein coupled receptor 35 ligand 6-chloro-8-[(2-fluoro-4-m... 3 9
G-protein coupled receptor 35 ligand 6-bromo-8-[(4-chlorobenzo... 3 7
Capsid scaffolding protein inhibitor AC1MHP1L family 3 6
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 4 1
Capsid scaffolding protein inhibitor AC1MHP20 family 3 3
Targeted effector protein and Tyrosine-protein phosphatase non... 2 2
Ras-related protein Rab-9A and Niemann-Pick C1 protein inhibit... 1 4


External ID

Functional Category

Molecule Name

CFAMM00441882 CHEMBL456495 Bioactive 3-acetamido-5-[2-(5-chloro-2-phenylmethoxyphenyl)phenyl]benzoic acid
CFAMM00441889 CHEMBL458452 Bioactive 3-[2-(5-chloro-2-phenylmethoxyphenyl)phenyl]-5-[(2-methoxyacetyl)amino]benzoic acid
CFAMM00441887 CHEMBL458448 Bioactive 3-[2-(5-chloro-2-phenylmethoxyphenyl)phenyl]-5-(2-methylpropanoylamino)benzoic acid
CFAMM00441885 CHEMBL516324 Bioactive 3-(butanoylamino)-5-[2-(5-chloro-2-phenylmethoxyphenyl)phenyl]benzoic acid
CFAMM00441883 CHEMBL456496 Bioactive 3-[2-(5-chloro-2-phenylmethoxyphenyl)phenyl]-5-(propanoylamino)benzoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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