CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17334
Family Name Acetylcholinesterase and Butyrylcholinesterase inhibitor 2-[4-[3-(diethylamino)propanoyl]phenoxy]-5,6-dimethoxy-2,3-dihydroinden-1-one family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00441906 Functional Category Bioactive
Superfamily Muscarinic acetylcholine receptor Ligand Mebeverine Superfamily
Class Class 333

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Muscarinic acetylcholine receptor Ligand Mebeverine Family 2 27
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Histamine H3 receptor ligand 1-(3,4-dimethoxyphenyl)-4-(4-pent... 2 0
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL14038... 1 9
Acetylcholinesterase inhibitor AGN-PC-003A5N family 3 9
Histamine H1 receptor ligand Ahr 5333 family 1 6
Neuronal acetylcholine receptor subunit alpha-7 ligand 2,7-bis... 3 0
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 2 20
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00441906 CHEMBL456967 Bioactive 2-[4-[3-(diethylamino)propanoyl]phenoxy]-5,6-dimethoxy-2,3-dihydroinden-1-one
CFAMM00441905 CHEMBL456968 Bioactive 2-[4-[3-[ethyl(methyl)amino]propanoyl]phenoxy]-5,6-dimethoxy-2,3-dihydroinden-1-one
CFAMM00441903 CHEMBL518384 Bioactive AGN-PC-077QNV

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27163 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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