CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17338
Family Name C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[ethyl-[2-(4-methylsulfonylphenyl)acetyl]amino]piperidin-1-yl]-1-phenylbutyl]cyclobutanecarboxamide family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00441921 Functional Category Bioactive
Superfamily C-C chemokine receptor type 5 Ligand AZD5672 Superfamily
Class Class 905

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
ATP-sensitive inward rectifier potassium channel 10 Ligand Ace... 2 64
Cathepsin K Inhibitor Odanacatib Family 33 84
C-C chemokine receptor type 5 Ligand AZD5672 Family 25 70
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
Integrin beta-3 Inhibitor L-750034 Family 7 38
Muscarinic acetylcholine receptor M2 Ligand SCH-211803 Family 3 6
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Cruzipain Inhibitor K-777 Family 3 8
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 1 0
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand N-(3-... 1 7
C-C chemokine receptor type 2 ligand SureCN2988733 family 14 17
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 2 5
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-3-methyl-... 3 4
Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745OU family 6 6
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 7 0
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
Acetylcholinesterase and Butyrylcholinesterase inhibitor N-[2-... 3 7
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 1
Acetylcholinesterase inhibitor N-[2-(1-benzylpiperidin-4-yl)et... 1 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 4
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[[2-(2,4-dic... 4 9
Sigma non-opioid intracellular receptor 1 ligand 2-(3-bromophe... 5 1
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 2 5
Oxytocin receptor and Vasopressin V2 receptor ligand (2R)-2-(2... 4 2
Cathepsin K and Cathepsin L1 inhibitor N-[1-(cyanomethylcarbam... 2 0
C-C chemokine receptor type 5 ligand AGN-PC-075XOD family 2 0
C-C chemokine receptor type 5 ligand AGN-PC-075XPW family 3 3
Cathepsin K and Cathepsin S inhibitor (1R,2R)-N-(cyanomethyl)-... 1 0
Receptor activity-modifying protein 1 and Calcitonin gene-rela... 2 4
Cannabinoid receptor 2 ligand AGN-PC-04VLWN family 9 4
Cannabinoid receptor 2 ligand N-cyclohexyl-4-propan-2-yl-3-pyr... 2 2
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
C-C chemokine receptor type 5 ligand N-[1-[(3R)-4-[benzenesulf... 3 1
Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-[2-(3-methy... 1 0
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-[(4-methylsul... 3 0
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhib... 5 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-... 1 0
Lethal(3)malignant brain tumor-like protein 3 and Lethal(3)mal... 1 0
Secreted frizzled-related protein 1 and Proto-oncogene Wnt-3 i... 2 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00441921 CHEMBL457043 Bioactive N-[(1S)-3-[4-[ethyl-[2-(4-methylsulfonylphenyl)acetyl]amino]piperidin-1-yl]-1-phenylbutyl]cyclobutanecarboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27074 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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