CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17346
Family Name Coagulation factor X inhibitor 3-chloroindole compound, 20 family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00441970 Functional Category Bioactive
Superfamily Coagulation factor X and Ceramide glucosyltransferase Binder Superfamily
Class Class 1033

Cousin Family NamesSeedsMembers
Growth hormone receptor Ligand EP-51216 Family 34 390
Lethal factor Inhibitor GM6001 Family 50 435
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Huntingtin and Glycogen synthase kinase-3 beta inhibitor SB 21... 2 4
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 1
Vascular endothelial growth factor receptor 2 and Receptor-typ... 7 4
cGMP-specific 3',5'-cyclic phosphodiesterase and Dual 3',5'-cy... 4 129
Bombesin receptor subtype-3 ligand SureCN13887096 family 3 1
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... 2 0
Receptor-interacting serine/threonine-protein kinase 1 ligand ... 1 11


External ID

Functional Category

Molecule Name

CFAMM00441966 CHEMBL516174 Bioactive 3-bromoindole compound, 21
CFAMM00441972 CHEMBL459141 Bioactive 3-chloroindole compound, 18
CFAMM00441970 CHEMBL515520 Bioactive 3-chloroindole compound, 20
CFAMM00441968 CHEMBL457702 Bioactive 3-chloroindole compound, 15

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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