CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17347
Family Name 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase inhibitor 1-[4-(2,6-dimethoxyphenyl)cyclohexyl]-4-pyridin-2-ylpiperazine family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00441976 Functional Category Bioactive
Superfamily D(2) dopamine receptor and Neuropeptide Y receptor type 1 Binder Superfamily
Class Class 513

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Histamine H1 receptor Ligand Mepyramine Family 5 65
Hypoxia-inducible factor 1-alpha Inhibitor Hif-1alpha Family 7 107
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Smoothened homolog Inhibitor LDE225 Family 3 76
Peptide deformylase, mitochondrial Inhibitor Epiroprim Family 5 68
Tissue-type plasminogen activator Inhibitor N-(7-benzyloxy-iso... 4 37
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 12 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
Metabotropic glutamate receptor 5 Ligand (3-ethoxy-pyridin-2-y... 3 12
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
5-hydroxytryptamine receptor 1A Ligand CP-293019 Family 9 24
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 4
Reverse transcriptase/RNaseH inhibitor AC1MHDM5 family 2 0
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor Sure... 14 8
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 7 16
Corticotropin-releasing factor receptor 1 ligand 8-(2-chloro-4... 13 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 3 14
TRAF2 and NCK-interacting protein kinase inhibitor 4-methoxy-3... 4 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 1
Alpha-1A adrenergic receptor and D(2) dopamine receptor ligand... 2 5
Nuclear receptor ROR-gamma and Cytochrome P450 3A4 ligand NCGC... 1 1
Corticotropin-releasing factor receptor 1 ligand N-(dicyclopro... 3 35


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00441976 CHEMBL457722 Bioactive 1-[4-(2,6-dimethoxyphenyl)cyclohexyl]-4-pyridin-2-ylpiperazine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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