CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17367
Family Name Macrophage colony-stimulating factor 1 receptor ligand AGN-PC-078VNK family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00442058 Functional Category Bioactive
Superfamily Huntingtin and Prelamin-A/C Binder Superfamily 32
Class Class 913

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Prothrombin Inhibitor Ximelegatran Family 8 157
Smoothened homolog Inhibitor Vismodegib Family 1 19
Histidine decarboxylase Inhibitor Bf-derm1 Family 12 95
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
Neuromedin-K receptor Ligand SB222200 Family 17 235
Glutamate receptor AMPA subtype Ligand CX-516 Family 9 24
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Substance-P receptor Ligand TAK-637 Family 18 63
ABC294640 family 5 75
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
XL-888 family 16 85
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-chlorophenyl)-5-... 2 8
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Amine oxidase [flavin-containing] B Inhibitor Lazebemide Family 2 13
Transient receptor potential cation channel subfamily V member... 6 23
Cannabinoid receptor 1 Ligand N-phenyl-5,6-dip-tolylpyrazine-2... 11 26
Peroxisome proliferator-activated receptor gamma Ligand 2-chlo... 5 19
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
RAC-alpha serine/threonine-protein kinase and Cyclin-dependent... 3 7
Vasopressin V2 receptor and Vasopressin V1a receptor ligand [2... 2 5
Rho-associated protein kinase 2 inhibitor N-(7-chloro-1-oxo-2H... 1 2
Survival motor neuron protein and Beta-lactamase inhibitor CHE... 1 0
Nicotinamide phosphoribosyltransferase inhibitor 4-[(7-chloro-... 6 4
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 1 1
Metabotropic glutamate receptor 2 and Metabotropic glutamate r... 5 3
Metabotropic glutamate receptor 2 ligand AGN-PC-00A1HD family 2 0
Acetylcholinesterase inhibitor CHEMBL1651131 family 6 9
Substance-K receptor ligand N-[1-[[(2R)-5-[4-(oxan-4-ylmethyl)... 2 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
Substance-P receptor and Neuromedin-K receptor ligand 2-[3,5-b... 7 0
Mast/stem cell growth factor receptor Kit and Mitogen-activate... 4 2
Melanin-concentrating hormone receptor 1 and 5-hydroxytryptami... 1 1
Tyrosine-protein kinase Lck and Vascular endothelial growth fa... 3 0
Beta-secretase 1 and Potassium voltage-gated channel subfamily... 2 11
Dual specificity protein kinase CLK4 and Mitogen-activated pro... 1 1
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 2
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 5 0
Coagulation factor X inhibitor AGN-PC-078Y0T family 11 0
Macrophage colony-stimulating factor 1 receptor ligand N-[3-[(... 5 0
P2X purinoceptor 7 inhibitor 2-chloro-N-[(1-hydroxy-3,3-dimeth... 1 8
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 1
C-X-C chemokine receptor type 2 ligand 6-chloro-N-(4-fluorophe... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00442058 CHEMBL459471 Bioactive AGN-PC-078VNK
CFAMM00442057 CHEMBL461365 Bioactive AGN-PC-078VNM

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27520 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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