CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17368
Family Name C-C chemokine receptor type 5 ligand (4-chlorophenyl) N-[1-[(4S)-4-(cyclobutanecarbonylamino)-4-phenylbutan-2-yl]piperidin-4-yl]-N-ethylcarbamate family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00442064 Functional Category Bioactive
Superfamily Lanosterol synthase and Hormone-sensitive lipase Binder Superfamily
Class Class 2862

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
Zucapsacin family 7 177
Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
Substance-P receptor Ligand Ezlopitant Family 10 207
5-hydroxytryptamine receptor 2A Ligand Pimavanserin Family 4 23
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Interstitial collagenase Inhibitor N-hydroxycarbamoylmethyl-4-... 5 24
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Acetylcholinesterase and Cholinesterase Inhibitor Caproctamine... 7 17
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Urotensin-2 receptor Ligand SB-436811 Family 6 71
D(2) dopamine receptor Ligand Epidepride Family 31 66
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Neutrophil elastase inhibitor (2S)-N-[(3S)-6-benzamido-5,5-dif... 6 10
Histamine H3 receptor ligand 1-(4-pentan-3-ylpiperazin-1-yl)-2... 1 1
3-hydroxyacyl-CoA dehydrogenase type-2 and Retinal dehydrogena... 1 15
Substance-P receptor ligand AGN-PC-075NP5 family 4 8
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 10
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Growth hormone secretagogue receptor type 1 ligand tert-butyl ... 5 4
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 3
Cytochrome P450 1A2 and Cytochrome P450 3A4 inhibitor 4-[4-[2-... 2 3
Potassium voltage-gated channel subfamily H member 2 and Melan... 5 4
Lanosterol synthase inhibitor (4-chlorophenyl) N-[4-[5-[ethyl(... 2 3
Cathepsin K and Cathepsin S inhibitor (1R,2R)-N-[cyano-(2-meth... 1 0
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 7 1
C-C chemokine receptor type 5 ligand 4-[4-[[4-[(5R)-3-cyclohex... 4 2
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 1
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 15
C-C chemokine receptor type 1 ligand SureCN8184421 family 11 10
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-(1,3-b... 4 2
Neuropeptide Y receptor type 1 and Sodium-dependent serotonin ... 2 7
Neuromedin-K receptor ligand SureCN2478117 family 1 0
Hormone-sensitive lipase inhibitor SureCN7550372 family 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00442062 CHEMBL518640 Bioactive (4-fluorophenyl) N-[1-[(4S)-4-(cyclobutanecarbonylamino)-4-phenylbutan-2-yl]piperidin-4-yl]-N-ethylcarbamate
CFAMM00442064 CHEMBL459567 Bioactive (4-chlorophenyl) N-[1-[(4S)-4-(cyclobutanecarbonylamino)-4-phenylbutan-2-yl]piperidin-4-yl]-N-ethylcarbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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