CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17377
Family Name Neuronal acetylcholine receptor subunit alpha-7 and Neuronal acetylcholine receptor subunit alpha-3 ligand (3R,5S)-5-[2-(1-benzofuran-5-yl)ethynyl]-1-methyl-3-(piperidin-1-ylmethyl)pyrrolidin-2-one family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00242197 Functional Category Bioactive with Natural Product
Superfamily Histamine H3 receptor and Prolyl endopeptidase Binder Superfamily
Class Class 769

Cousin Family NamesSeedsMembers
Muscarinic acetylcholine receptor M3 Ligand Darifenacin Family 3 17
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 8 66
Histamine H3 receptor Ligand A-349821 Family 49 228
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 33
Melatonin receptor type 1A and Melatonin receptor type 1B Liga... 33 98
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 4 62
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 5 0
Histamine H3 receptor ligand SureCN2784769 family 12 2
Histamine H3 receptor ligand SureCN2785131 family 7 1
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 7 18
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00442121 CHEMBL503427 Bioactive (3R,5S)-5-[2-(2,3-dihydro-1-benzofuran-5-yl)ethynyl]-1-methyl-3-(piperidin-1-ylmethyl)pyrrolidin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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