CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17379
Family Name Mitogen-activated protein kinase 14 inhibitor SureCN828349 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00442130 Functional Category Bioactive
Superfamily Histamine H3 receptor and Inositol monophosphatase 1 Binder Superfamily 2
Class Class 145

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Histamine H3 receptor and Histamine H4 receptor Ligand Clobenp... 31 38
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family 3 33
Interleukin-1 receptor type 1 and Mitogen-activated protein ki... 7 151
Beta-secretase 1 Inhibitor 6-[2-(1h-indol-6-yl)ethyl]pyridin-2... 10 43
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2,6-di... 13 14
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... 3 16
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
Indoleamine 2,3-dioxygenase 1 Inhibitor 3-(4h-imidazol-4-yl)be... 6 3
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Sterol O-acyltransferase 1 inhibitor 1-(2,4-difluorophenyl)-3-... 8 90
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase inh... 7 6
Mitogen-activated protein kinase 14 inhibitor (E)-3-(2,6-dichl... 1 1
Mitogen-activated protein kinase 14 inhibitor AGN-PC-03XQYG fa... 7 1
Somatostatin receptor type 5 and Somatostatin receptor type 2 ... 6 3
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2152398 family 16 1
CGMP-dependent protein kinase inhibitor SureCN14561191 family 4 0
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 16 0
Serine/threonine-protein kinase mTOR inhibitor 1-ethyl-3-[4-[6... 4 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
C-C chemokine receptor type 3 and Cytochrome P450 2D6 ligand 1... 1 0
Gonadotropin-releasing hormone receptor ligand AGN-PC-00AWCA f... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00442130 CHEMBL459926 Bioactive SureCN828349

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26236 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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