CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17385
Family Name Transient receptor potential cation channel subfamily V member 1 ligand 2-N-(2,6-dichlorophenyl)-7-N-[4-(trifluoromethyl)phenyl]-[1,3]thiazolo[5,4-d]pyrimidine-2,7-diamine family
No. of Seeds 9 No. of Other Members 13
Family Centroid CFAMM00418779 Functional Category Bioactive
Superfamily Transient receptor potential cation channel subfamily V member 1 and Epidermal growth factor receptor Binder Superfamily
Class Class 3543

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase A Inhibitor CYC116 Family 16 135
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 4 23
Aurora kinase B and Aurora kinase A inhibitor AGN-PC-07ZBLC fa... 3 8
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(4-acet... 4 12
Vascular endothelial growth factor receptor 2 and Mast/stem ce... 10 27
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M88D fa... 2 1
Mitogen-activated protein kinase 14 and LIM domain kinase 1 in... 4 19
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 5 27
Fatty-acid amide hydrolase 1 inhibitor 5-[5-(4-chlorophenyl)su... 2 4
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(1,4-di... 3 3
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 5-[5-chloro-... 2 18
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 7
Tyrosine-protein kinase Lck inhibitor AGN-PC-074MSE family 18 2
Vascular endothelial growth factor receptor 2 ligand Thienopyr... 2 2
Transient receptor potential cation channel subfamily V member... 1 1
Transient receptor potential cation channel subfamily V member... 2 0
Epidermal growth factor receptor ligand AGN-PC-077TJS family 3 5
Epidermal growth factor receptor ligand AGN-PC-00RWHW family 3 4
Transient receptor potential cation channel subfamily V member... 1 0
Transient receptor potential cation channel subfamily V member... 1 0
Epidermal growth factor receptor and Receptor tyrosine-protein... 2 1
Aurora kinase A and Vascular endothelial growth factor recepto... 1 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00442179 CHEMBL512298 Bioactive 2-N-(2,6-dichlorophenyl)-7-N-(4-propan-2-ylphenyl)-[1,3]thiazolo[5,4-d]pyrimidine-2,7-diamine
CFAMM00442171 CHEMBL517566 Bioactive AGN-PC-04T7ZL
CFAMM00442184 CHEMBL468470 Bioactive AGN-PC-04T87A
CFAMM00442169 CHEMBL465990 Bioactive AGN-PC-04T89R
CFAMM00442174 CHEMBL460373 Bioactive AGN-PC-04T8F3

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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