CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17388
Family Name Sodium- and chloride-dependent glycine transporter 1 inhibitor AGN-PC-00CT4G family
No. of Seeds 10 No. of Other Members 14
Family Centroid CFAMM00442188 Functional Category Bioactive
Superfamily Sodium- and chloride-dependent glycine transporter 1 Binder Superfamily 5
Class Class 4843

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Substance-P receptor Ligand TAK-637 Family 18 63
ABC294640 family 5 75
Potassium voltage-gated channel subfamily H member 2 Ligand E-... 1 4
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
D(4) dopamine receptor Ligand ABT-670 Family 4 14
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Peroxisome proliferator-activated receptor delta Ligand GSK-37... 1 10
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6R... 2 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 2 3
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 1
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 1 0
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 4 1
Oxytocin receptor ligand 3-[(1R,3S,4S)-7,7-dimethyl-4-(spiro[1... 2 1
Calpain-1 catalytic subunit inhibitor 2,5-dichloro-N-[(2S)-3,4... 2 0


External ID

Functional Category

Molecule Name

CFAMM00442190 CHEMBL518340 Bioactive AGN-PC-00DXXG
CFAMM00442203 CHEMBL460537 Bioactive SureCN3566742
CFAMM00442202 CHEMBL464087 Bioactive AGN-PC-00AFH5
CFAMM00442195 CHEMBL464508 Bioactive AGN-PC-00AA7U
CFAMM00442208 CHEMBL464088 Bioactive AGN-PC-00CSMM
CFAMM00442188 CHEMBL465428 Bioactive AGN-PC-00CT4G
CFAMM00442201 CHEMBL484733 Bioactive AGN-PC-00D8NS
CFAMM00442200 CHEMBL484734 Bioactive AGN-PC-00CTC7
CFAMM00442211 CHEMBL461986 Bioactive AGN-PC-078XHA
CFAMM00442197 CHEMBL518070 Bioactive AGN-PC-00AF5W

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



67825 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543