CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM174
Family Name Somatostatin receptor type 4 and Glucosylceramidase ligand MLS002703100 family
No. of Seeds 1 No. of Other Members 16
Family Centroid CFAMM00308373 Functional Category Bioactive
Superfamily Platelet-activating factor receptor and Glucosylceramidase Binder Superfamily
Class Class 2257

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
Benzodiazepine receptor Ligand Midazolam Family 5 160
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
HCV NS4B protein Inhibitor Clemizole Family 2 43
Histamine H3 receptor and Histamine H4 receptor Ligand Clobenp... 31 38
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Histamine H3 receptor Ligand SCH79687 Family 11 29
Adenosine receptor A3 Ligand 2,6-bis(4-chlorophenyl)-9h-purine... 4 12
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Adenosine receptor A3 Ligand 2-(5-chloro-1h-benzo[d]imidazol-2... 7 51
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Aromatase and Cytochrome P450 26A1 Inhibitor Liarozole Family 4 1
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family 5 6
Glycogen synthase kinase-3 beta Inhibitor 4-(5-bromo-1h-indol-... 7 18
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... 3 0
Histamine H3 receptor Ligand 4-(2-(phenylamino)ethyl)-1h-imida... 5 16
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 5 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 1
Methionine--tRNA ligase inhibitor N-[(4R)-6,8-dibromo-1,2,3,4-... 1 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 6 3
Mitogen-activated protein kinase 10 inhibitor CYCLOPROPYL-{4-[... 2 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00308373 CHEMBL103769 Bioactive MLS002703100

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27256 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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