CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17412
Family Name Orexin receptor type 2 and Orexin receptor type 1 ligand (2R)-2-[8-[2-(3,4-dimethylphenyl)ethyl]-3-ethyl-1-methoxy-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00442337 Functional Category Bioactive
Superfamily Orexin receptor type 2 and Orexin receptor type 1 Binder Superfamily 6
Class Class 86

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 21 32
Orexin receptor type 2 and Orexin receptor type 1 ligand (2R)-... 12 16


External ID

Functional Category

Molecule Name

CFAMM00442338 CHEMBL462433 Bioactive (2R)-2-[(8S)-3-ethyl-8-[2-(3-fluoro-4-methylphenyl)ethyl]-1-methoxy-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
CFAMM00442337 CHEMBL461772 Bioactive (2R)-2-[8-[2-(3,4-dimethylphenyl)ethyl]-3-ethyl-1-methoxy-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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