CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17416
Family Name Sodium-dependent noradrenaline transporter inhibitor SureCN4084324 family
No. of Seeds 5 No. of Other Members 12
Family Centroid CFAMM00442371 Functional Category Bioactive
Superfamily Sodium-dependent noradrenaline transporter and Mineralocorticoid receptor Binder Superfamily
Class Class 933

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Nociceptin receptor Ligand J-113397 Family 3 14
Androgen receptor Ligand YM-175735 Family 30 129
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Induced myeloid leukemia cell differentiation protein Mcl-1 an... 2 7
Pol polyprotein inhibitor AC1LAMTL family 11 15
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 11 9
Pol polyprotein inhibitor DMP-450 family 9 4
Histamine H3 receptor and Histamine receptor H3 ligand 1-cyclo... 3 4
Beta-secretase 1 and Cathepsin D inhibitor (4S)-N-[(2S,3R)-4-[... 3 0
Neuropeptide Y receptor type 5 ligand 3-(4-benzylphenyl)-1-[(1... 2 4
Sodium-dependent dopamine transporter and Sigma non-opioid int... 3 10
Sodium-dependent noradrenaline transporter and Sodium-dependen... 12 16
DNA polymerase III PolC-type inhibitor HB-EMAU family 17 7


External ID

Functional Category

Molecule Name

CFAMM00442366 CHEMBL560877 Bioactive SureCN4080780
CFAMM00442372 CHEMBL551474 Bioactive SureCN4077243
CFAMM00442365 CHEMBL564229 Bioactive SureCN4076967
CFAMM00442371 CHEMBL551473 Bioactive SureCN4084324
CFAMM00442376 CHEMBL462313 Bioactive Zilpaterol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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