CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17421
Family Name Vesicular acetylcholine transporter inhibitor (2R,3R)-5-(3-fluoropropoxy)-3-(4-phenylpiperidin-1-yl)-1,2,3,4-tetrahydronaphthalen-2-ol family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00442383 Functional Category Bioactive
Superfamily Estrogen receptor and Estrogen receptor beta Binder Superfamily 13
Class Class 142

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Delta-type opioid receptor ligand opiate analog Codeine Family 15 184
u-type opioid receptor ligand opiate analog Buprenorphine Family 78 234
Beta adrenergic receptor ligand naphthol derivative Propranolo... 11 218
u-type opioid receptor ligand opiate opiate analog Oxymorphone... 22 105
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Opioid receptor ligand opiate Levorphanol Family 18 537
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
5-hydroxytryptamine receptor 2A Ligand Sarpogrelate Family 2 15
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Acolbifene family 10 115
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Fibroblast growth factor receptor Ligand SU5403 Family 8 8
Histamine H3 receptor Ligand UCL-2138 Family 23 172
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 41
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
5-hydroxytryptamine receptor 2A and D(1A) dopamine receptor Li... 8 33
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Renin Inhibitor Ro-65-7219 Family 10 8
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 44 3
D(2) dopamine receptor and D(1A) dopamine receptor Ligand 3-ch... 2 0
Kappa-type opioid receptor Ligand Morphinan Cyclic Imine Analo... 20 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 12
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 2 1
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 6 5
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 2
Mu-type opioid receptor and Sigma non-opioid intracellular rec... 10 20
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 8
Sodium-dependent dopamine transporter and Sodium-dependent ser... 6 0
D(2) dopamine receptor and D(1A) dopamine receptor ligand ISOM... 2 5
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 8 2
Estrogen receptor and Estrogen receptor beta ligand (2R,3R,4S)... 3 0
Histamine H3 receptor ligand cyclohexyl-[4-(3-piperidin-1-ylpr... 4 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Kappa-type opioid receptor ligand CHEMBL2367762 family 2 0
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-00E... 7 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 3 6
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00442383 CHEMBL462659 Bioactive (2R,3R)-5-(3-fluoropropoxy)-3-(4-phenylpiperidin-1-yl)-1,2,3,4-tetrahydronaphthalen-2-ol
CFAMM00442382 CHEMBL510679 Bioactive (2R,3R)-5-[(E)-3-iodoprop-2-enoxy]-3-(4-phenylpiperidin-1-yl)-1,2,3,4-tetrahydronaphthalen-2-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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