CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17427
Family Name Nuclear receptor subfamily 1 group I member 2 ligand AGN-PC-078YU1 family
No. of Seeds 2 No. of Other Members 13
Family Centroid CFAMM00442412 Functional Category Bioactive
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Inhibitor XL147 Superfamily
Class Class 857

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Mizolastine Family 14 603
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Type-2 angiotensin II receptor Ligand L-158282 Family 24 58
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 6 60
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Growth hormone secretagogue receptor type 1 and Dihydrofolate ... 3 6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
Cannabinoid receptor 2 ligand 2-tert-butyl-5-ethylsulfonyl-1-(... 28 32
Aurora kinase B and Vascular endothelial growth factor recepto... 1 2
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand N-[1-... 5 3
Cannabinoid receptor 2 ligand 4-[[2-tert-butyl-1-(cyclohexylme... 2 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 0
Carbonic anhydrase 2 and Carbonic anhydrase 9 inhibitor ZINC00... 1 0
5-hydroxytryptamine receptor 2B ligand SureCN1299053 family 1 1
Dipeptidyl peptidase 4 and Potassium voltage-gated channel sub... 1 0
Nucleotide-binding oligomerization domain-containing protein 1... 2 1
Prothrombin inhibitor SureCN3000235 family 2 4
D(2) dopamine receptor and D(4) dopamine receptor ligand 3-[1-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00442408 CHEMBL464497 Bioactive AGN-PC-078YTI
CFAMM00442412 CHEMBL463678 Bioactive AGN-PC-078YU1

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27425 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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