CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1743
Family Name P2X purinoceptor 7 inhibitor N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-2-(3,5-dimethyl-1,2-oxazol-4-yl)acetamide family
No. of Seeds 2 No. of Other Members 20
Family Centroid CFAMM00327032 Functional Category Bioactive
Superfamily Prelamin-A/C and P2X purinoceptor 7 Binder Superfamily
Class Class 3442

Cousin Family NamesSeedsMembers
Amine oxidase [flavin-containing] A inhibitor hydrazine antide... 1 1
Cystic fibrosis transmembrane conductance regulator and Anocta... 12 74
DNA-(apurinic or apyrimidinic site) lyase and Menin inhibitor ... 1 18
Transient receptor potential cation channel subfamily V member... 7 36
Transient receptor potential cation channel subfamily V member... 12 0
Protease inhibitor AC1O53DF family 8 1
C-C chemokine receptor type 5 ligand N-[(1S)-3-[(3aS,6aR)-5-(3... 1 1


External ID

Functional Category

Molecule Name

CFAMM00327034 CHEMBL2094242 Bioactive AGN-PC-046WIF
CFAMM00327032 CHEMBL1210623 Bioactive N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-2-(3,5-dimethyl-1,2-oxazol-4-yl)acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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