CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17431
Family Name Prostaglandin E2 receptor EP3 subtype ligand N-(benzenesulfonyl)-2-[(3-naphthalen-2-ylsulfanyl-1H-indol-4-yl)oxy]acetamide family
No. of Seeds 17 No. of Other Members 15
Family Centroid CFAMM00442454 Functional Category Bioactive
Superfamily D(4) dopamine receptor and D(2) dopamine receptor Binder Superfamily 3
Class Class 3729

Cousin Family NamesSeedsMembers
Apricoxib family 8 77
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... 3 3
Prostaglandin E2 receptor EP3 subtype ligand (E)-3-(1-methyl-4... 14 12
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,5-dichlo... 2 9
Prostaglandin E2 receptor EP3 subtype ligand N-(4,5-dichloroth... 22 3
Prostaglandin E2 receptor EP3 subtype ligand AGN-PC-0790SA family 2 0
Prostaglandin E2 receptor EP3 subtype ligand (E)-3-[4-(4-chlor... 7 0


External ID

Functional Category

Molecule Name

CFAMM00442433 CHEMBL479427 Bioactive N-(4,5-dichlorothiophen-2-yl)sulfonyl-2-[(3-naphthalen-2-ylsulfonyl-1H-indol-4-yl)oxy]acetamide
CFAMM00442444 CHEMBL480992 Bioactive N-(3,5-difluorophenyl)sulfonyl-2-[(3-naphthalen-2-ylsulfonyl-1H-indol-4-yl)oxy]acetamide
CFAMM00442426 CHEMBL520425 Bioactive AGN-PC-0790VA
CFAMM00442450 CHEMBL481782 Bioactive N-(5-chlorothiophen-2-yl)sulfonyl-2-[(3-naphthalen-2-ylsulfonyl-1H-indol-4-yl)oxy]acetamide
CFAMM00442432 CHEMBL516708 Bioactive AGN-PC-0790UB
CFAMM00442440 CHEMBL520290 Bioactive 2-[(3-naphthalen-2-ylsulfanyl-1H-indol-4-yl)oxy]-N-thiophen-2-ylsulfonylacetamide
CFAMM00442454 CHEMBL464063 Bioactive N-(benzenesulfonyl)-2-[(3-naphthalen-2-ylsulfanyl-1H-indol-4-yl)oxy]acetamide
CFAMM00442425 CHEMBL481589 Bioactive N-(3,5-dichlorophenyl)sulfonyl-2-[(3-naphthalen-2-ylsulfanyl-1H-indol-4-yl)oxy]acetamide
CFAMM00442449 CHEMBL481004 Bioactive N-(3,5-difluorophenyl)sulfonyl-2-[(3-naphthalen-2-ylsulfanyl-1H-indol-4-yl)oxy]acetamide
CFAMM00442431 CHEMBL517165 Bioactive N-(5-chlorothiophen-2-yl)sulfonyl-2-[(3-naphthalen-2-ylsulfanyl-1H-indol-4-yl)oxy]acetamide
CFAMM00442430 CHEMBL517180 Bioactive AGN-PC-0790TB
CFAMM00442438 CHEMBL464031 Bioactive N-(3-chlorophenyl)sulfonyl-2-[(3-naphthalen-2-ylsulfanyl-1H-indol-4-yl)oxy]acetamide
CFAMM00442447 CHEMBL465947 Bioactive N-(4-methoxyphenyl)sulfonyl-2-[(3-naphthalen-2-ylsulfanyl-1H-indol-4-yl)oxy]acetamide
CFAMM00442428 CHEMBL466184 Bioactive AGN-PC-0790IB
CFAMM00442436 CHEMBL464032 Bioactive N-(4,5-dichlorothiophen-2-yl)sulfonyl-2-[(3-naphthalen-2-ylsulfanyl-1H-indol-4-yl)oxy]acetamide
CFAMM00442427 CHEMBL482380 Bioactive N-(2-chlorophenyl)sulfonyl-2-[(3-naphthalen-2-ylsulfanyl-1H-indol-4-yl)oxy]acetamide
CFAMM00442451 CHEMBL482379 Bioactive N-(2,5-dimethoxyphenyl)sulfonyl-2-[(3-naphthalen-2-ylsulfanyl-1H-indol-4-yl)oxy]acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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