CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17437
Family Name Histamine H3 receptor ligand AGN-PC-00AE5Q family
No. of Seeds 13 No. of Other Members 13
Family Centroid CFAMM00442532 Functional Category Bioactive with Human Metabolite & Natural Product
Superfamily Histamine H3 receptor and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily 4
Class Class 3845

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
Extracellular calcium-sensing receptor Ligand 2-furan-2-yl-3-p... 4 119
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-methoxy-phenyl)-... 1 3
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 28 91
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Prelamin-A/C and Survival motor neuron protein inhibitor CHEMB... 1 7
Vasopressin V1b receptor ligand AGN-PC-09QGT9 family 4 123
Vasopressin V1b receptor ligand AGN-PC-00HJ2S family 4 6
Growth hormone secretagogue receptor type 1 ligand (2R)-N-(1-b... 11 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 2
Dipeptidyl peptidase 4 and Cytochrome P450 3A4 inhibitor SureC... 2 3
C-X-C chemokine receptor type 3 ligand N-(2-ethoxyethyl)-N-[(1... 1 1
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 10
Ghrelin/growth hormone secretagogue receptor and Cytochrome P4... 5 20
Coagulation factor X and Trypsin-1 inhibitor SureCN7484452 family 3 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 16 2
Histamine H3 receptor ligand AGN-PC-03Z8FM family 5 0
Histamine H3 receptor and Potassium voltage-gated channel subf... 28 30
Histamine H3 receptor ligand AGN-PC-03Z8HJ family 4 1
5-hydroxytryptamine receptor 7 ligand 4-[4-(2-ethoxyphenyl)pip... 2 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00442547 CHEMBL483400 Bioactive SureCN502064
CFAMM00442526 CHEMBL485543 Bioactive SureCN119942
CFAMM00442539 CHEMBL487063 Bioactive SureCN4464071
CFAMM00442532 CHEMBL483199 Bioactive AGN-PC-00AE5Q
CFAMM00442538 CHEMBL478395 Bioactive SureCN4470400
CFAMM00442545 CHEMBL483366 Bioactive AGN-PC-00DMOT
CFAMM00442537 CHEMBL517937 Bioactive SureCN502360
CFAMM00442523 CHEMBL516697 Bioactive SureCN4462908
CFAMM00442536 CHEMBL464599 Bioactive SureCN502675
CFAMM00442522 CHEMBL484189 Bioactive SureCN502523
CFAMM00442542 CHEMBL485389 Bioactive AGN-PC-04X2W9
CFAMM00442534 CHEMBL484946 Bioactive SureCN502383
CFAMM00442549 CHEMBL464598 Bioactive SureCN502215

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27518 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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